Unveiling the hidden therapeutic potential of carnosine, a molecule with a multimodal mechanism of action: A position paper

G Caruso - Molecules, 2022 - mdpi.com
Carnosine (β-alanyl-L-histidine) is a naturally occurring endogenous dipeptide and an over-
the-counter food supplement with a well-demonstrated multimodal mechanism of action that …

Protective effect of Panax ginseng against serum biochemical changes and apoptosis in liver of rats treated with carbon tetrachloride (CCl4)

E Karakus, A Karadeniz, N Simsek, I Can… - Journal of hazardous …, 2011 - Elsevier
The purpose of this study was to investigate possible beneficial effects of Panax ginseng
(PG) on carbon tetrachloride (CCl4)-induced acute hepatotoxicity in rats. CCl4 challenge …

Biochemical and histopathological study in rats intoxicated with carbontetrachloride and treated with camel milk

T Althnaian, I Albokhadaim, SM El-Bahr - SpringerPlus, 2013 - Springer
The unique characters of camel's milk make it used extensively in the field of medicine as
anti-microbial, anti-diabetic and hepatoprotective agent. The lack of studies demonstrating …

Carbon tetrachloride-induced hepatotoxicity in rat is reversed by treatment with riboflavin

NO Al-Harbi, F Imam, A Nadeem, MM Al-Harbi… - International …, 2014 - Elsevier
Liver is a vital organ for the detoxification of toxic substances present in the body and
hepatic injury is associated with excessive exposure to toxicants. The present study was …

Effect of Tinospora crispa on thioacetamide-induced liver cirrhosis in rats

FA Kadir, F Othman, MA Abdulla… - Indian journal of …, 2011 - journals.lww.com
Objectives: This study was conducted to determine the effect of ethanolic extract of the dried
stems of Tinospora crispa in a male rat model of hepatic fibrosis caused by the hepatotoxin …

The effect of carnosine treatment on prooxidant–antioxidant balance in liver, heart and brain tissues of male aged rats

AF Aydın, C Küçükgergin, G Özdemirler-Erata… - Biogerontology, 2010 - Springer
Abstract Carnosine (β-alanyl-l-histidine) is a dipeptide with antioxidant properties. Oxidative
damage by free radicals is one of the mechanisms underlying the aging process. This study …

Effects of α-lipoic acid and L-carnosine supplementation on antioxidant activities and lipid profiles in rats

MY Kim, EJ Kim, YN Kim, C Choi… - Nutrition research and …, 2011 - synapse.koreamed.org
α-Lipoic acid and L-carnosine are powerful antioxidants and are often used as a health
supplement and as an ergogenic aid. The objective of this study was to investigate the …

Hepatoprotective effects of the xanthine oxidase inhibitor Febuxostat against thioacetamide-induced liver injury in rats: The role of the Nrf2/HO-1 and TLR4/NF-κB …

RS Abdelrahman, ME Abdelmageed - Food and Chemical Toxicology, 2024 - Elsevier
Experimental models of liver injury have been established utilizing thioacetamide (TAA), a
classic liver toxic chemical that causes organ damage via oxidative stress and inflammatory …

Effect of carnosine against thioacetamide-induced liver cirrhosis in rat

AF Aydın, Z Küskü-Kiraz, S Doğru-Abbasoğlu… - Peptides, 2010 - Elsevier
Carnosine (β-alanyl-l-histidine) is a dipeptide with antioxidant properties. Oxidative stress
has been proposed to be involved in thioacetamide (TAA)-induced liver cirrhosis in rats, that …

Carnosine ameliorates liver fibrosis and hyperammonemia in cirrhotic rats

A Jamshidzadeh, R Heidari, Z Latifpour… - Clinics and Research in …, 2017 - Elsevier
Aim Chronic liver injury and cirrhosis leads to liver failure. Hyperammonemia is a
deleterious consequence of liver failure. On the other hand, oxidative stress seems to play a …