Regulation of antigen uptake, migration, and lifespan of dendritic cell by Toll-like receptors

I Zanoni, F Granucci - Journal of molecular medicine, 2010 - Springer
Dendritic cells (DCs) sense the presence of pathogens through germline-encoded pattern
recognition receptors (PRRs), which recognize molecular patterns expressed by various …

Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells

M Kleijmeer, G Ramm, D Schuurhuis, J Griffith… - The Journal of cell …, 2001 - rupress.org
Immature dendritic cells (DCs) sample their environment for antigens and after stimulation
present peptide associated with major histocompatibility complex class II (MHC II) to naive T …

In situ replication of immediate dendritic cell (DC) precursors contributes to conventional DC homeostasis in lymphoid tissue

J Diao, E Winter, C Cantin, W Chen, L Xu… - The Journal of …, 2006 - journals.aai.org
The developmental biology of dendritic cells (DC) under physiological conditions remains
unclear. In this study, we show that mouse CD11c+ MHC class II− lineage− cells are …

Altered expression and endocytic function of CD205 in human dendritic cells, and detection of a CD205–DCL‐1 fusion protein upon dendritic cell maturation

M Butler, AS Morel, WJ Jordan, E Eren, S Hue… - …, 2007 - Wiley Online Library
Summary CD205 (DEC‐205) is a member of the macrophage mannose receptor family of C‐
type lectins. These molecules are known to mediate a wide variety of biological functions …

Quantum Dots for Tracking Dendritic Cells and Priming an Immune Response In Vitro and In Vivo

D Sen, TJ Deerinck, MH Ellisman, I Parker… - PloS one, 2008 - journals.plos.org
Dendritic cells (DCs) play a key role in initiating adaptive immune response by presenting
antigen to T cells in lymphoid organs. Here, we investigate the potential of quantum dots …

Composition of MHC class II-enriched lipid microdomains is modified during maturation of primary dendritic cells

N Setterblad, C Roucard, C Bocaccio… - Journal of Leucocyte …, 2003 - academic.oup.com
Dendritic cells (DCs) are the most potent antigen presenting cells. Major histocompatibility
complex (MHC) class II molecule expression changes with maturation; immature DCs …

Gene-modified dendritic cells for immunotherapy against cancer

A Lundqvist, P Pisa - Medical Oncology, 2002 - Springer
Dendritic cells (DCs) are described as professional antigen-presenting cells because of their
superior T-cell stimulatory capacity. For this reason, attention is being focused on using DCs …

Dendritic cells: interfaces with immunobiology and medicine. A report from the Keystone Symposia Meeting held in Keystone, 3–8 March 2003

M Mohty, B Gaugler - Leukemia, 2003 - nature.com
Dendritic cells (DCs) are the most potent antigen-presenting cells in vitro and in vivo. They
play a key role in the initiation of the immune response and are considered promising …

Rapid downregulation of antigen processing enzymes in ex vivo generated human monocyte derived dendritic cells occur endogenously in extended cultures

RK Ishri, S Menzies, P Hersey… - Immunology and cell …, 2004 - Wiley Online Library
Dendritic cells, the most potent antigen presenting cells, have been shown in murine models
to induce immune responses against many antigens. Their role in the initiation of antitumour …

[PDF][PDF] The Role of MERTK in Central Inflammatory Demyelination

CM Dwyer - 2020 - minerva-access.unimelb.edu.au
Multiple sclerosis (MS) is, at least in part, an autoimmune demyelinating disease of the
central nervous system. It is the most common cause of neurological dysfunction in young …