Motile cells inside living tissues often encounter junctions, where their path branches into
several alternative directions of migration. We present a theoretical model of cellular …

Motile cells encounter microenvironments with locally heterogeneous mechanochemical
composition. Individual compositional parameters, such as chemokines and extracellular …

The cell’s dilemma: resolving directional decisions: Trends in Immunology Skip to Main Content
Advertisement Trends in Immunology This journal offers authors two options (open access or …

Cell crawling on flat substrates stems from intracellular flows of the actin cytoskeleton that
are driven by both actin polymerization at the front and myosin contractility at the back …

To move through complex environments, cells must constantly integrate chemical and
mechanical cues. Signaling networks, such as those comprising Ras and PI3K, transmit …

Actin dynamics mediate cell morphogenesis and motility. Actin filaments polymerise outward
at cell protrusions such as the leading edge of migrating cells, thereby pushing the …