A bacterial effector reveals the V-ATPase-ATG16L1 axis that initiates xenophagy

Y Xu, P Zhou, S Cheng, Q Lu, K Nowak, AK Hopp, L Li… - Cell, 2019 - cell.com
Antibacterial autophagy (xenophagy) is an important host defense, but how it is initiated is
unclear. Here, we performed a bacterial transposon screen and identified a T3SS effector …

Genetic mechanisms of antibiotic resistance and the role of antibiotic adjuvants

DS Pontes, RSA de Araujo, N Dantas… - Current topics in …, 2018 - ingentaconnect.com
The ever increasing number of multidrug-resistant microorganism pathogens has become a
great and global public health threat. Antibiotic mechanisms of action and the opposing …

The Yersinia Type III Secretion System as a Tool for Studying Cytosolic Innate Immune Surveillance

KA Schubert, Y Xu, F Shao… - Annual Review of …, 2020 - annualreviews.org
Microbial pathogens have evolved complex mechanisms to interface with host cells in order
to evade host defenses and replicate. However, mammalian innate immune receptors detect …

Different subtypes of influenza viruses target different human proteins and pathways leading to different pathogenic phenotypes

Y Wang, T Song, K Li, Y Jin, J Yue… - BioMed research …, 2019 - Wiley Online Library
Different subtypes of influenza A viruses (IAVs) cause different pathogenic phenotypes after
infecting human bodies. Analysis of the interactions between viral proteins and the host …