Mitochondrial genomes revisited: why do different lineages retain different genes?
The mitochondria contain their own genome derived from an alphaproteobacterial
endosymbiont. From thousands of protein-coding genes originally encoded by their …
endosymbiont. From thousands of protein-coding genes originally encoded by their …
Is the mutation rate lower in genomic regions of stronger selective constraints?
A study of the plant Arabidopsis thaliana detected lower mutation rates in genomic regions
where mutations are more likely to be deleterious, challenging the principle that …
where mutations are more likely to be deleterious, challenging the principle that …
[HTML][HTML] Spontaneous and environment induced genomic alterations in yeast model
KJ Li, L Qi, YX Zhu, M He, Q Xiang, DQ Zheng - Cell Insight, 2024 - Elsevier
While genomic alterations are fundamental to biological evolution, enabling adaptation and
diversity, they can also result in detrimental outcomes, such as the development of genetic …
diversity, they can also result in detrimental outcomes, such as the development of genetic …
Two independent DNA repair pathways cause mutagenesis in template switching deficient Saccharomyces cerevisiae
YK Jiang, EA Medley, GW Brown - Genetics, 2023 - academic.oup.com
Upon DNA replication stress, cells utilize the postreplication repair pathway to repair single-
stranded DNA and maintain genome integrity. Postreplication repair is divided into 2 …
stranded DNA and maintain genome integrity. Postreplication repair is divided into 2 …
Aurantiochytrium mutant strains exhibiting different colony colors altered the contents of squalene
T Yang, S Kubo, DJ Juntila, Y Iwata… - Bioscience …, 2024 - academic.oup.com
Abstract Aurantiochytrium sp. 18W-13a, a marine heterotrophic protist belonging to the
genus thraustochytrid, is known to accumulate high levels of squalene and carotenoids …
genus thraustochytrid, is known to accumulate high levels of squalene and carotenoids …
Spontaneous single-nucleotide substitutions and microsatellite mutations have distinct distributions of fitness effects
The fitness effects of new mutations determine key properties of evolutionary processes.
Beneficial mutations drive evolution, yet selection is also shaped by the frequency of small …
Beneficial mutations drive evolution, yet selection is also shaped by the frequency of small …
Mutations in yeast are deleterious on average regardless of the degree of adaptation to the testing environment
K Bao, BR Strayer, NP Braker, AA Chan… - Proceedings …, 2024 - royalsocietypublishing.org
The role of spontaneous mutations in evolution depends on the distribution of their effects on
fitness. Despite a general consensus that new mutations are deleterious on average, a …
fitness. Despite a general consensus that new mutations are deleterious on average, a …