Many types of human cells self-destruct to maintain biological homeostasis and defend the
body against pathogenic substances. This process, called regulated cell death (RCD), is …

In recent years, neutrophils have attracted increasing attention because of their cancer-
promoting effects. An elevated neutrophil-to-lymphocyte ratio is considered a prognostic …

Ferroptosis is a non-apoptotic form of regulated cell death that is triggered by the
discoordination of regulatory redox mechanisms culminating in massive peroxidation of …

Tightly orchestrated programmed cell death (PCD) signalling events occur during normal
neuronal development in a spatially and temporally restricted manner to establish the neural …

Ferroptosis, a cell death modality characterized by iron-dependent lipid peroxidation, is
involved in the development of multiple pathological conditions, including ischemic tissue …

Glioblastoma (GBM) is one of the most aggressive and lethal solid tumors in human. While
efficacious therapeutics, such as emerging chimeric antigen receptor (CAR)-T cells and …

Obesity is closely related to a poor prognosis in patients with advanced colorectal cancer
(CRC), but the mechanisms remain unclear. Ferroptosis is a form of nonapoptotic cell death …

Neutrophils are abundant immune cells in the circulation and frequently infiltrate tumors in
substantial numbers. However, their precise functions in different cancer types remain …

Tissues are organized in cellular niches, the composition and interactions of which can be
investigated using spatial omics technologies. However, systematic analyses of tissue …

Accumulating evidence shows that deregulation of fatty acid (FA) metabolism is associated
with the development of cancer. Long-chain acyl-coenzyme A synthases (ACSLs) are …