Aggregation‐induced emission (AIE) has attracted considerable interest over the last twenty
years. In contrast to the large number of available reviews focusing specifically on AIE, this …

Small-molecule fluorophores manifest the ability of chemistry to solve problems in biology.
As we noted in a previous review (Lavis, LD; Raines, RT ACS Chem. Biol. 2008, 3, 142 …

Gaining greater understanding of the structural and functional properties of living systems is
a key challenge in biology and medicine. On a more practical side, the diagnosis and …

Because RNA lacks strong intrinsic fluorescence, it has proven challenging to track RNA
molecules in real time. To address this problem and to allow the purification of fluorescently …

We describe a simple, quantitative assay for any amplifiable DNA sequence that uses a
video camera to monitor multiple polymerase chain reactions (PCRs) simultaneously over …

The most fundamental questions such as whether a cell is alive, in the sense of being able
to divide or to form a colony, may sometimes be very hard to answer, since even axenic …

DNA is the central storage molecule of genetic information in the cell, and reading that
information is a central problem in biology. While sequencing technology has made …

The breakthroughs in single molecule spectroscopy of the last decade and the recent
advances in super resolution microscopy have boosted the popularity of cyanine dyes in …

We report evidence that gene complexes, consisting of polycations and plasmid DNA enter
cells via binding to membrane-associated proteoglycans. Treatment of HeLa cells with …

Fluorescence spectroscopy is widely used in biological research. Until recently, essentially
all fluorescence experiments were performed using optical energy which has radiated to the …