The design of small-molecule prodrugs and activatable phototherapeutics for cancer therapy

HH Han, HM Wang, P Jangili, M Li, L Wu… - Chemical Society …, 2023 - pubs.rsc.org
Cancer remains as one of the most significant health problems, with approximately 19
million people diagnosed worldwide each year. Chemotherapy is a routinely used method to …

Fluorescent probes for the detection of disease-associated biomarkers

WT Dou, HH Han, AC Sedgwick, GB Zhu, Y Zang… - Science Bulletin, 2022 - Elsevier
Fluorescent probes have emerged as indispensable chemical tools to the field of chemical
biology and medicine. The ability to detect intracellular species and monitor physiological …

J‐Aggregation Strategy toward Potentiated NIR‐II Fluorescence Bioimaging of Molecular Fluorophores

X Hu, C Zhu, F Sun, Z Chen, J Zou, X Chen… - Advanced …, 2024 - Wiley Online Library
Molecular fluorophores emitting in the second near‐infrared (NIR‐II, 1000–1700 nm)
window with strong optical harvesting and high quantum yields hold great potential for in …

Targeted contrast agents and activatable probes for photoacoustic imaging of cancer

Z Zhao, CB Swartchick, J Chan - Chemical Society Reviews, 2022 - pubs.rsc.org
Photoacoustic (PA) imaging has emerged as a powerful technique for the high resolution
visualization of biological processes within deep tissue. Through the development and …

Discovery of BODIPY J-aggregates with absorption maxima beyond 1200 nm for biophotonics

X Wang, Z Jiang, Z Liang, T Wang, Y Chen, Z Liu - Science Advances, 2022 - science.org
Organic dyes with absorption maxima in the second near-infrared window (NIR-II; 1000 to
1700 nm) are of great interest in biophotonics. However, because of the lack of appropriate …

Stimuli‐responsive organic near‐infrared photoacoustic probes

Q Shen, L Wang, X Ruan, N Li, W Wang… - Advanced Functional …, 2023 - Wiley Online Library
Photoacoustic (PA) imaging is an emerging biomedical imaging technique with the features
of non‐invasiveness and non‐ionization. It takes advantage of the photothermal effect of PA …

Recent progress in metal complexes functionalized nanomaterials for photodynamic therapy

F Wei, Z Chen, XC Shen, L Ji, H Chao - Chemical Communications, 2023 - pubs.rsc.org
Metal complexes have shown promise as photosensitizers for cancer diagnosis and
therapeutics. However, the vast majority of metal photosensitizers are not ideal and …

Background-suppressed tumor-targeted photoacoustic imaging using bacterial carriers

R Gao, F Liu, W Liu, S Zeng, J Chen… - Proceedings of the …, 2022 - National Acad Sciences
Photoacoustic (PA) imaging offers promise for biomedical applications due to its ability to
image deep within biological tissues while providing detailed molecular information; …

Plasmon enhanced catalysis-driven nanomotors with autonomous navigation for deep cancer imaging and enhanced radiotherapy

L Liu, Q Li, L Chen, L Song, X Zhang, H Huo, Z You… - Chemical …, 2022 - pubs.rsc.org
Radiosensitizers potentiate the radiotherapy effect while effectively reducing the damage to
healthy tissues. However, limited sample accumulation efficiency and low radiation energy …

J-aggregates of Br-and piperazine-modified cyanine dye with the assistance of amphiphilic polypeptides for efficient NIR-IIa phototheranostics under 1064 nm …

C Teng, H Dang, S Zhang, Y Xu, D Yin, L Yan - Acta Biomaterialia, 2022 - Elsevier
The second near-infrared IIa window (NIR-IIa, 1300nm∼ 1400nm) enables high-resolution
imaging and deep-tissue tumor treatment due to its unique low tissue scattering and …