Child and adolescent obesity

NB Lister, LA Baur, JF Felix, AJ Hill, C Marcus… - Nature Reviews …, 2023 - nature.com
The prevalence of child and adolescent obesity has plateaued at high levels in most high-
income countries and is increasing in many low-income and middle-income countries …

Epigenetics in human obesity and type 2 diabetes

C Ling, T Rönn - Cell metabolism, 2019 - cell.com
Epigenetic mechanisms control gene activity and the development of an organism. The
epigenome includes DNA methylation, histone modifications, and RNA-mediated processes …

Obesity pathogenesis: an endocrine society scientific statement

MW Schwartz, RJ Seeley, LM Zeltser… - Endocrine …, 2017 - academic.oup.com
Obesity is among the most common and costly chronic disorders worldwide. Estimates
suggest that in the United States obesity affects one-third of adults, accounts for up to one …

Obesity subtypes, related biomarkers & heterogeneity

LPC Mayoral, GM Andrade, EPC Mayoral… - Indian Journal of …, 2020 - journals.lww.com
Obesity is a serious medical condition worldwide, which needs new approaches and
recognized international consensus in treating diseases leading to morbidity. The aim of this …

Association of body mass index with DNA methylation and gene expression in blood cells and relations to cardiometabolic disease: a Mendelian randomization …

MM Mendelson, RE Marioni, R Joehanes, C Liu… - PLoS …, 2017 - journals.plos.org
Background The link between DNA methylation, obesity, and adiposity-related diseases in
the general population remains uncertain. Methods and Findings We conducted an …

Recent progress in epigenetics of obesity

FY Wu, RX Yin - Diabetology & Metabolic Syndrome, 2022 - Springer
Nowadays, obesity is one of the largest public health problems worldwide. In the last few
decades, there has been a marked increase in the obesity epidemic and its related …

Birth size as a determinant of cardiometabolic risk factors in children

H Nordman, J Jääskeläinen… - Hormone Research in …, 2020 - karger.com
The association between birth size and cardiometabolic disease risk may be U-shaped.
Being born small for gestational age (SGA) has a definitive association with later …

Genetics, epigenetics and transgenerational transmission of obesity in children

N Panera, C Mandato, A Crudele… - Frontiers in …, 2022 - frontiersin.org
Sedentary lifestyle and consumption of high-calorie foods have caused a relentless increase
of overweight and obesity prevalence at all ages. Its presently epidemic proportion is …

Epigenetics, obesity and early-life cadmium or lead exposure

SS Park, DA Skaar, RL Jirtle, C Hoyo - Epigenomics, 2017 - Taylor & Francis
Obesity is a complex and multifactorial disease, which likely comprises multiple subtypes.
Emerging data have linked chemical exposures to obesity. As organismal response to …

DNA methylation and obesity traits: An epigenome-wide association study. The REGICOR study

S Sayols-Baixeras, I Subirana, A Fernández-Sanlés… - Epigenetics, 2017 - Taylor & Francis
Obesity is associated with increased risk of several diseases and has become epidemic.
Obesity is highly heritable but the genetic variants identified by genome-wide association …