Osteoarthritis (OA) is an age-related cartilage degenerative disease, and chondrocyte
senescence has been extensively studied in recent years. Increased numbers of senescent …

Aging attenuates the overall responsiveness of the immune system to eradicate pathogens.
The increased production of pro-inflammatory cytokines by innate immune cells under basal …

Emerging evidences have highlighted the crucial role of microRNAs (miRNAs) in the liver
cirrhosis, but the relationship between miR-130a-3p and liver cirrhosis is not entirely clear …

Mesenchymal stem cells (MSCs)-derived exosomes were considered a novel therapeutic
approach in many aging-related diseases. This study aimed to clarify the protective effects of …

Liver cancer is the 7 th utmost frequent neoplasm and the 4 th principal source of cancer
deaths. This malignancy is linked with several environmental and lifestyle-related factors …

Epidemiological data highlight prostate cancer as a significant global health issue, with high
incidence and substantial impact on patients' quality of life. The prevalence of this disease is …

Cancer treatment has been associated with accelerated aging that can lead to early-onset
health complications typically experienced by older populations. In particular, cancer …

Abstract Alzheimer's disease (AD), the most common type of dementia, is a serious
neurodegenerative disease that has no cure yet, but whose symptoms can be alleviated with …

It is becoming clear that the DNA damage response orchestrates an appropriate response to
a given level of DNA damage, whether that is cell cycle arrest and repair, senescence or …

Exosomes are the main actors of intercellular communications and have gained great
interest in the new cell-free regenerative medicine. These nanoparticles are secreted by …