Recent advances in the clinical value and potential of dexmedetomidine

X Liu, Y Li, L Kang, Q Wang - Journal of Inflammation Research, 2021 - Taylor & Francis
Dexmedetomidine, a highly selective α2-adrenoceptor agonist, has sedative, anxiolytic,
analgesic, sympatholytic, and opioid-sparing properties and induces a unique sedative …

[HTML][HTML] Effect of 5-μg dose of dexmedetomidine in combination with intrathecal bupivacaine on spinal anesthesia: a systematic review and meta-analysis

S Liu, P Zhao, Y Cui, C Lu, M Ji, W Liu, W Jiang… - Clinical Therapeutics, 2020 - Elsevier
Purpose Intrathecal dexmedetomidine (DEX) has been used to improve the quality and
duration of spinal anesthesia. The aim of this meta-analysis is to evaluate whether …

Comparison of the ED50 of intrathecal hyperbaric ropivacaine co-administered with or without intrathecal dexmedetomidine for cesarean section: A prospective …

Y Tang, M Yang, F Fu, X Huang, Y Feng… - Journal of Clinical …, 2020 - Elsevier
Study objective Studies have showed that intrathecal dexmedetomidine as supplements to
local anesthetics can improve the quality of the spinal anesthesia and reduce the local …

Intravenous dexmedetomidine for the treatment of shivering during cesarean delivery under neuraxial anesthesia: a randomized-controlled trial

C Lamontagne, S Lesage, E Villeneuve… - Obstetric Anesthesia …, 2020 - journals.lww.com
Neuraxial anesthesia is preferable for cesarean deliveries (CDs), as it allows mothers to be
awake and avoids the associated risks of general anesthesia. However, an estimated 53 …

[Retracted] The Anesthetic Effect and Safety of Dexmedetomidine in Cesarean Section: A Meta‐Analysis

G Pang, Y Zhu, Y Zhou, S Tong - BioMed Research …, 2022 - Wiley Online Library
Objective. To evaluate the anesthetic effect and safety of dexmedetomidine in cesarean
section. Methods. The Cochrane Library, EMBASE, and PubMed databases (established …

Effect of intrathecal dexmedetomidine on preventing shivering in cesarean section after spinal anesthesia: a meta-analysis and trial sequential analysis

S Miao, M Shi, L Zou, G Wang - Drug Design, Development and …, 2018 - Taylor & Francis
Objective Intrathecal dexmedetomidine (DEX) has been used to prevent shivering in
patients undergoing cesarean section. The aim of this meta-analysis was to evaluate …

Effect of intrathecal dexmedetomidine on cesarean section during spinal anesthesia: a meta-analysis of randomized trials

YQ Wang, XJ Zhang, Y Wang - Drug design, development and …, 2019 - Taylor & Francis
Objective Intrathecal dexmedetomidine has been used in spinal anesthesia during cesarean
sections. The purpose of this meta-analysis was to investigate the effect of intrathecal …

Intrathecal dexmedetomidine as an adjuvant to plain ropivacaine for spinal anesthesia during cesarean section: a prospective, double-blinded, randomized trial for …

X Mo, F Huang, X Wu, J Feng, J Zeng, J Chen - BMC anesthesiology, 2023 - Springer
Background Intrathecal dexmedetomidine, as an adjuvant to local anesthetics, has been
reported to improve the quality of spinal anesthesia and reduce the required local anesthetic …

Dexmedetomidine as an adjuvant for single spinal anesthesia in patients undergoing cesarean section: a system review and meta-analysis

Q Shen, H Li, X Zhou, X Yuan… - Journal of International …, 2020 - journals.sagepub.com
Objective Previous studies reported the effect of dexmedetomidine on intrathecal
anesthesia. In this review, we explored the impact of dexmedetomidine as an adjunct for …

Comparative evaluation of intrathecal bupivacaine alone and bupivacaine combined with dexmedetomidine in cesarean section using spinal anesthesia: a meta …

X Liu, X Zhang, X Wang, J Wang… - Journal of International …, 2019 - journals.sagepub.com
Objective This meta-analysis was performed to evaluate the effect of spinal anesthesia (SA)
using bupivacaine combined with dexmedetomidine (DEX) in cesarean section, analyze the …