Abstract Significance: The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-
specific protein and the upregulated expression of this receptor is one of the major changes …

Antibiotic resistance is a major and increasing healthcare problem that threatens many of
the achievements of modern medicine. Transplants, chemotherapy, and survival of …

African Americans have higher rates of kidney disease than European Americans. Here, we
show that, in African Americans, focal segmental glomerulosclerosis (FSGS) and …

The role of mammalian skin in harbouring and transmitting arthropod-borne protozoan
parasites has been overlooked for decades as these pathogens have been regarded …

Intercellular communication between parasites and with host cells provides mechanisms for
parasite development, immune evasion, and disease pathology. Bloodstream African …

Abstract Studies on Variant Surface Glycoproteins (VSGs) and antigenic variation in the
African trypanosome, Trypanosoma brucei, have yielded a remarkable range of novel and …

This paper reviews the transmission modes of Trypanosoma evansi. Its worldwide
distribution is attributed to mechanical transmission. While the role of tabanids is clear, we …

The trypanosomiases consist of a group of important animal and human diseases caused by
parasitic protozoa of the genus Trypanosoma. In sub-Saharan Africa, the final decade of the …

Kinetoplastids are a group of flagellated protozoans that include the species Trypanosoma
and Leishmania, which are human pathogens with devastating health and economic effects …

Human sleeping sickness in east Africa is caused by the parasite Trypanosoma brucei
rhodesiense. The basis of this pathology is the resistance of these parasites to lysis by …