Mesenchymal stem cells (MSCs) are among the most investigated and applied somatic stem
cells in experimental therapies for the regeneration of damaged tissues. Moreover, as it was …

Progress in the treatment of small cell lung cancer (SCLC) has been modest over the past
decades until the advent of immune checkpoint inhibitors, which have redefined the …

It is well accepted that the tumor microenvironment plays a pivotal role in cancer onset,
development, and progression. The majority of clinical interventions are designed to target …

Background Glioma is the most prevalent brain tumor with high mortality and morbidity and
the prognosis of patients remains very poor. Glioma therapy is largely limited by the …

Purpose: Mesenchymal stem cells (MSC) have emerged as cellular-based vehicles for the
delivery of therapeutic genes in cancer therapy based on their inherent tumor-homing …

Immune checkpoint blockade (ICB) necessitates a thorough understanding of intricate
cellular interactions within the tumor microenvironment (TME). Mesenchymal stromal cells …

Glioblastoma multiforme (GBM) is the most common and lethal primary tumor of the central
nervous system. What makes it so dreadful is the very low survival rate, despite the …

Purpose The cone-beam computed tomography (CBCT)–guided small animal radiation
research platform (SARRP) has provided unique opportunities to test radiobiologic …

Background Epithelial ovarian cancer is the leading cause of death from gynecologic
cancer, in which serous ovarian carcinoma (SOC) is the most common histological subtype …

The inherent homing ability toward tumor sites of mesenchymal stem cells (MSCs) after
systemic delivery has, during the past decade, created an impetus to develop these stem …