Monofluorination of organic compounds: 10 years of innovation

PA Champagne, J Desroches, JD Hamel… - Chemical …, 2015 - ACS Publications
Taking into account the vast arrays of fluorinated motifs known, 11 this review will be limited
to the monofluorination of organic compounds, ie, synthetic methods allowing the …

Trihaloisocyanuric acids: Useful reagents for halogenation reactions and heterocyclic scaffold construction

MCS de Mattos - Current Organic Chemistry, 2024 - benthamdirect.com
Trihaloisocyanuric acids [1, 3, 5-trihalo-1, 3, 5-triazine-2, 4, 6-(1H, 3H, 5H)-triones] are
commercially available or easily prepared solids. They are highly reactive, stable, easily …

Trichloroisocyanuric acid promoted cascade cyclization/trifluoromethylation of allylic oximes: Synthesis of trifluoromethylated isoxazolines

W Zhang, Y Su, KH Wang, L Wu, B Chang, Y Shi… - Organic …, 2017 - ACS Publications
Cheap and commercially available trichloroisocyanuric acid has been used to promote
trifluoromethylation by using TMSCF3 as the trifluoromethyl source. The method provides a …

Palladium-catalyzed iodofluorination of alkenes using fluoro-iodoxole reagent

NO Ilchenko, MA Cortes, KJ Szabo - Acs Catalysis, 2016 - ACS Publications
The application of an air-and moisture-stable fluoroiodane reagent was investigated in the
palladium-catalyzed iodofluorination reaction of alkenes. Both the iodo and fluoro …

Diastereodivergent nucleophile–nucleophile alkene chlorofluorination

S Doobary, AJD Lacey, SG Sweeting, SB Coppock… - Nature Chemistry, 2024 - nature.com
The selective hetero-dihalogenation of alkenes provides useful building blocks for a broad
range of chemical applications. Unlike homo-dihalogenation, selective hetero …

The double halofluorination reaction of alkynes using trihaloisocyanuric acids and Olah's reagent

HS Bragueroli, PM Esteves, MCS de Mattos - Journal of Fluorine Chemistry, 2023 - Elsevier
A simple and efficient method to produce a CF 2 group vicinal to a CX 2 group (X= chlorine
or bromine) through double halofluorination reaction of alkynes using trihaloisocyanuric acid …

Synthesis of α-hydroxy fatty acids from fatty acids by intermediate α-chlorination with TCCA under solvent-free conditions: A way to valorization of waste fat biomasses

V Bertolini, M Pallavicini, G Tibhe, G Roda, S Arnoldi… - ACS …, 2021 - ACS Publications
Within food wastes, including edible and inedible parts, fat biomasses represent a significant
portion, often uneconomically used or improperly disposed causing pollution issues …

Recent developments in the fluorofunctionalization of alkenes

XH Xu, FL Qing - Current Organic Chemistry, 2015 - benthamdirect.com
The difunctionalization of unsaturated carbon-carbon double bond is a powerful strategy for
the construction of compounds with various functional groups. The present review aims to …

Tribromoisocyanuric acid in trifluoroacetic acid: an efficient system for smooth brominating of moderately deactivated arenes

LS de Almeida, MCS de Mattos, PM Esteves - Synlett, 2013 - thieme-connect.com
Moderately deactivated arenes are efficiently brominated by the reaction with
tribromoisocyanuric acid (0.34 mol equiv) in trifluoroacetic acid at room temperature in 48 …

On the halofluorination reactions of olefins as selective, and an efficient methodology for the introduction of fluorine into organic molecules

B Marciniak, J Walkowiak-Kulikowska… - Journal of Fluorine …, 2017 - Elsevier
Monofluorinated organic compounds play a crucial role in the design of new drugs and
biologically active compounds; especially if they contain another halogen atom which can …