Pathophysiology of Post-COVID syndromes: a new perspective

GES Batiha, HM Al-Kuraishy, AI Al-Gareeb, NN Welson - Virology Journal, 2022 - Springer
Most COVID-19 patients recovered with low mortality; however, some patients experienced
long-term symptoms described as “long-COVID” or “Post-COVID syndrome”(PCS). Patients …

Regulation of short-chain fatty acids in the immune system

X Liu, J Shao, YT Liao, LN Wang, Y Jia… - Frontiers in …, 2023 - frontiersin.org
A growing body of research suggests that short-chain fatty acids (SCFAs), metabolites
produced by intestinal symbiotic bacteria that ferment dietary fibers (DFs), play a crucial role …

Treatment of peanut allergy and colitis in mice via the intestinal release of butyrate from polymeric micelles

R Wang, S Cao, MEH Bashir, LA Hesser, Y Su… - Nature Biomedical …, 2023 - nature.com
The microbiome modulates host immunity and aids the maintenance of tolerance in the gut,
where microbial and food-derived antigens are abundant. Yet modern dietary factors and …

Dietary fiber and SCFAs in the regulation of mucosal immunity

JK Tan, L Macia, CR Mackay - Journal of allergy and clinical immunology, 2023 - Elsevier
Gut bacterial metabolites such as short-chain fatty acids (SCFAs) have important effects on
immune cells and the gut. SCFAs derive from the fermentation of dietary fiber by gut …

Butyrate shapes immune cell fate and function in allergic asthma

W Yip, MR Hughes, Y Li, A Cait, M Hirst… - Frontiers in …, 2021 - frontiersin.org
The microbiome plays a fundamental role in how the immune system develops and how
inflammatory responses are shaped and regulated. The “gut-lung axis” is a relatively new …

Perinatal and early-life nutrition, epigenetics, and allergy

N Acevedo, B Alashkar Alhamwe, L Caraballo, M Ding… - Nutrients, 2021 - mdpi.com
Epidemiological studies have shown a dramatic increase in the incidence and the
prevalence of allergic diseases over the last several decades. Environmental triggers …

Role of dietary fiber in promoting immune health—An EAACI position paper

C Venter, RW Meyer, M Greenhawt, I Pali‐Schöll… - Allergy, 2022 - Wiley Online Library
Microbial metabolism of specific dietary components, such as fiber, contributes to the
sophisticated inter‐kingdom dialogue in the gut that maintains a stable environment with …

Decoding the genetic and epigenetic basis of asthma

BS Stikker, RW Hendriks, R Stadhouders - Allergy, 2023 - Wiley Online Library
Asthma is a complex and heterogeneous chronic inflammatory disease of the airways.
Alongside environmental factors, asthma susceptibility is strongly influenced by genetics …

Lung immune tone via gut-lung axis: gut-derived LPS and short-chain fatty acids' immunometabolic regulation of lung IL-1β, FFAR2, and FFAR3 expression

Q Liu, X Tian, D Maruyama… - American Journal of …, 2021 - journals.physiology.org
Microbial metabolites produced by the gut microbiome, eg short-chain fatty acids (SCFA),
have been found to influence lung physiology and injury responses. However, how lung …

The role of short-chain fatty acids in inflammatory skin diseases

X Xiao, X Hu, J Yao, W Cao, Z Zou, L Wang… - Frontiers in …, 2023 - frontiersin.org
Short-chain fatty acids (SCFAs) are metabolites of gut microbes that can modulate the host
inflammatory response, and contribute to health and homeostasis. Since the introduction of …