Background The relationship between psychotic disorders and cannabis use is heavily
debated. Shared underlying genetic risk is one potential explanation. We investigated the …

Genetic risks for schizophrenia are theoretically mediated by genetic effects on brain
structure but it has been unclear which genes are associated with both schizophrenia and …

Improved understanding of the shared genetic architecture between psychiatric disorders
and brain white matter may provide mechanistic insights for observed phenotypic …

Background Immune mechanisms are indicated in schizophrenia (SCZ). Recent genome-
wide association studies (GWAS) have identified genetic variants associated with SCZ and …

Transcriptome-wide association studies (TWAS) aim to detect relationships between gene
expression and a phenotype, and are commonly used for secondary analysis of genome …

Abstract Background Patients with Parkinson's disease (PD) have consistently demonstrated
brain structure abnormalities, indicating the presence of shared etiological and pathological …

Background The cerebellum is recognized as being involved in neurocognitive and motor
functions with communication with extra-cerebellar regions relying on the white matter …

BackgroundOver the past several decades, more research focuses have been made on the
inflammation/immune hypothesis of schizophrenia. Building upon synaptic plasticity …

Genome-wide association studies suggest significant overlaps in Parkinson's disease (PD)
and schizophrenia (SZ) risks, but the underlying mechanisms remain elusive. The protein …

Genetic pleiotropy is abundant across spatially distributed brain characteristics derived from
one neuroimaging modality (eg structural, functional or diffusion magnetic resonance …