Eslicarbazepine acetate: a new improvement on a classic drug family for the treatment of partial-onset seizures

GL Galiana, AC Gauthier, RH Mattson - Drugs in R&D, 2017 - Springer
Eslicarbazepine acetate is a new anti-epileptic drug belonging to the dibenzazepine
carboxamide family that is currently approved as adjunctive therapy and monotherapy for …

[HTML][HTML] Pharmacogenetics of adverse reactions to antiepileptic drugs

I Fricke-Galindo, H Jung-Cook, A LLerena… - Neurología (English …, 2018 - Elsevier
Abstract Introduction Adverse drug reactions (ADRs) are a major public health concern and
a leading cause of morbidity and mortality in the world. In the case of antiepileptic drugs …

Long-term safety and efficacy of eslicarbazepine acetate in patients with focal seizures: results of the 1-year ESLIBASE retrospective study

V Villanueva, JM Serratosa, E Guillamón, M Garcés… - Epilepsy research, 2014 - Elsevier
Background Eslicarbazepine acetate (ESL) is a new antiepileptic drug (AED) licensed as
adjunctive therapy in adults with partial-onset or focal seizures. Objective To evaluate in a …

Dibenzazepine agents in epilepsy: how does eslicarbazepine acetate differ?

C Lawthom, J Peltola, R McMurray, E Dodd… - Neurology and …, 2018 - Springer
Abstract Carbamazepine (CBZ), oxcarbazepine (OXC), and eslicarbazepine acetate (ESL)
belong to the dibenzazepine family of antiepileptic drugs and are all thought to primarily act …

Euro-Esli: a European audit of real-world use of eslicarbazepine acetate as a treatment for partial-onset seizures

V Villanueva, M Holtkamp, N Delanty… - Journal of …, 2017 - Springer
Abstract The Euro-Esli study was an exploratory pooled analysis of data from 14 European
clinical practice studies, which was conducted to audit the real-world effectiveness, safety …

Perspectives on treatment options for mesial temporal lobe epilepsy with hippocampal sclerosis

C Palleria, A Coppola, R Citraro… - Expert Opinion on …, 2015 - Taylor & Francis
Introduction: Mesial temporal lobe epilepsy associated with hippocampal sclerosis (MTLE-
HS) is a syndrome that is often refractory to drug treatment. The effects on specific …

Clinical utility of eslicarbazepine: current evidence

G Zaccara, F Giovannelli, M Cincotta… - Drug design …, 2015 - Taylor & Francis
Eslicarbazepine acetate (ESL) is a new antiepileptic drug whose mechanism of action is
blockade of the voltage-gated sodium channel (VGSC). However, in respect to …

Eslicarbazepine acetate in the treatment of adults with partial-onset epilepsy: an evidence-based review of efficacy, safety and place in therapy

S Lattanzi, F Brigo, C Cagnetti, A Verrotti… - Core …, 2018 - Taylor & Francis
Introduction: Up to 30% of the patients diagnosed with epilepsy will continue suffering from
seizures despite treatment with antiepileptic drugs, either in monotherapy or polytherapy …

Eslicarbazepine acetate: an update on efficacy and safety in epilepsy

A Verrotti, G Loiacono, A Rossi, G Zaccara - Epilepsy research, 2014 - Elsevier
Epilepsy is a common neurological disorder. Despite a broad range of commonly used
antiepileptic drugs, approximately 30% of patients with epilepsy have drug resistance or …

Practical guidance and considerations for transitioning patients from oxcarbazepine or carbamazepine to eslicarbazepine acetate—Expert opinion

J Peltola, M Holtkamp, R Rocamora, P Ryvlin… - Epilepsy & Behavior, 2015 - Elsevier
There is currently a lack of guidance on methodology and special considerations for
transitioning patients from oxcarbazepine (OXC) or carbamazepine (CBZ) to …