Abstract Introduction Adverse drug reactions (ADRs) are a major public health concern and a leading cause of morbidity and mortality in the world. In the case of antiepileptic drugs …
V Villanueva, JM Serratosa, E Guillamón, M Garcés… - Epilepsy research, 2014 - Elsevier
Background Eslicarbazepine acetate (ESL) is a new antiepileptic drug (AED) licensed as adjunctive therapy in adults with partial-onset or focal seizures. Objective To evaluate in a …
C Lawthom, J Peltola, R McMurray, E Dodd… - Neurology and …, 2018 - Springer
Abstract Carbamazepine (CBZ), oxcarbazepine (OXC), and eslicarbazepine acetate (ESL) belong to the dibenzazepine family of antiepileptic drugs and are all thought to primarily act …
V Villanueva, M Holtkamp, N Delanty… - Journal of …, 2017 - Springer
Abstract The Euro-Esli study was an exploratory pooled analysis of data from 14 European clinical practice studies, which was conducted to audit the real-world effectiveness, safety …
C Palleria, A Coppola, R Citraro… - Expert Opinion on …, 2015 - Taylor & Francis
Introduction: Mesial temporal lobe epilepsy associated with hippocampal sclerosis (MTLE- HS) is a syndrome that is often refractory to drug treatment. The effects on specific …
G Zaccara, F Giovannelli, M Cincotta… - Drug design …, 2015 - Taylor & Francis
Eslicarbazepine acetate (ESL) is a new antiepileptic drug whose mechanism of action is blockade of the voltage-gated sodium channel (VGSC). However, in respect to …
S Lattanzi, F Brigo, C Cagnetti, A Verrotti… - Core …, 2018 - Taylor & Francis
Introduction: Up to 30% of the patients diagnosed with epilepsy will continue suffering from seizures despite treatment with antiepileptic drugs, either in monotherapy or polytherapy …
A Verrotti, G Loiacono, A Rossi, G Zaccara - Epilepsy research, 2014 - Elsevier
Epilepsy is a common neurological disorder. Despite a broad range of commonly used antiepileptic drugs, approximately 30% of patients with epilepsy have drug resistance or …
There is currently a lack of guidance on methodology and special considerations for transitioning patients from oxcarbazepine (OXC) or carbamazepine (CBZ) to …