Prognostic factors of biochemical remission after transsphenoidal surgery for acromegaly: a structured review

N Agrawal, AG Ioachimescu - Pituitary, 2020 - Springer
Purpose Biochemical control is the main determinant of survival, clinical manifestations and
comorbidities in acromegaly. Transsphenoidal selective adenomectomy (TSA) is the initial …

Microsurgical versus endoscopic transsphenoidal resection for acromegaly: a systematic review of outcomes and complications

CJ Chen, N Ironside, IJ Pomeraniec, S Chivukula… - Acta …, 2017 - Springer
Purpose The aim of this systematic review is to evaluate the long-term endocrine outcomes
and postoperative complications following endoscopic vs. microscopic transsphenoidal …

Changing presentation of acromegaly in half a century: a single-center experience

AN Demir, C Sulu, Z Kara, S Sahin, D Ozaydin… - Pituitary, 2023 - Springer
Objective Investigate the changes in the characteristics of presentation, in patients with
acromegaly over a period of approximately half a century. Methods The medical records of …

The prognostic-based approach in growth hormone-secreting pituitary neuroendocrine tumors (PitNET): Tertiary reference center, single senior surgeon, and long …

A Ferrés, L Reyes, A Di Somma, T Topczewski… - Cancers, 2022 - mdpi.com
Simple Summary Pituitary neuroendocrine tumors (PitNET) are characterized to present a
heterogeneous behavior, and growth hormone (GH)-secreting PitNET is not an exception …

Effectiveness and safety of pegvisomant: a systematic review and meta-analysis of observational longitudinal studies

LP Leonart, FS Tonin, VL Ferreira, F Fernandez-Llimos… - Endocrine, 2019 - Springer
Purpose Acromegaly is a rare disease that often requires drug treatment to achieve control,
with pegvisomant being one of the most widely used therapies. In the present paper, we …

Impact of tumor characteristics and pre-and postoperative hormone levels on hormonal remission following endoscopic transsphenoidal surgery in patients with …

T Cardinal, MJ Rutkowski, A Micko, M Shiroishi… - Neurosurgical …, 2020 - thejns.org
OBJECTIVE Acromegaly is a disease of acral enlargement and elevated serum levels of
insulin-like growth factor–1 (IGF-1) and growth hormone (GH), usually caused by a pituitary …

Machine learning as a clinical decision support tool for patients with acromegaly

C Sulu, AB Bektaş, S Şahin, E Durcan, Z Kara… - Pituitary, 2022 - Springer
Objective To develop machine learning (ML) models that predict postoperative remission,
remission at last visit, and resistance to somatostatin receptor ligands (SRL) in patients with …

A follow-up study on outcomes of endoscopic transsphenoidal approach for acromegaly

S Aydin, B Ozoner, S Sahin, O Alizada… - Clinical Neurology and …, 2020 - Elsevier
Objective A thorough follow-up study in which the same clinic presents the change in the
surgical outcomes of acromegaly over the years, is still lacking in the endoscopic era. In this …

Surgical results and predictors of initial and delayed remission for growth hormone-secreting pituitary adenomas using the 2010 consensus criteria in 162 patients …

M Shen, Y Tang, X Shou, M Wang, Q Zhang, N Qiao… - World Neurosurgery, 2019 - Elsevier
Background The factors associated with initial and delayed remission after growth hormone
(GH)-secreting pituitary adenoma excision have not been completely elucidated. Methods …

India's march towards development of treatment for pituitary tumors

P Gupta, M Tripathi, S Dhandapani, P Dutta - Neurology India, 2020 - journals.lww.com
Background: Although low-and middle-income countries (LMIC) bear the burden of the
pituitary adenomas, most research is conducted in developed countries. However, there has …