Immune responses to stroke: mechanisms, modulation, and therapeutic potential

C Iadecola, MS Buckwalter… - The Journal of clinical …, 2020 - Am Soc Clin Investig
Stroke is the second leading cause of death worldwide and a leading cause of disability.
Most strokes are caused by occlusion of a major cerebral artery, and substantial advances …

Global brain inflammation in stroke

K Shi, DC Tian, ZG Li, AF Ducruet, MT Lawton… - The Lancet …, 2019 - thelancet.com
Stroke, including acute ischaemic stroke and intracerebral haemorrhage, results in neuronal
cell death and the release of factors such as damage-associated molecular patterns …

Post-stroke dementia–a comprehensive review

MD Mijajlović, A Pavlović, M Brainin, WD Heiss… - BMC medicine, 2017 - Springer
Post-stroke dementia (PSD) or post-stroke cognitive impairment (PSCI) may affect up to one
third of stroke survivors. Various definitions of PSCI and PSD have been described. We …

Neuroinflammation in acute ischemic and hemorrhagic stroke

DL Alsbrook, M Di Napoli, K Bhatia, J Biller… - Current neurology and …, 2023 - Springer
Abstract Purpose of Review This review aims to provide an overview of neuroinflammation
in ischemic and hemorrhagic stroke, including recent findings on the mechanisms and …

Neuroinflammation as a key driver of secondary neurodegeneration following stroke?

SM Stuckey, LK Ong, LE Collins-Praino… - International Journal of …, 2021 - mdpi.com
Ischaemic stroke involves the rapid onset of focal neurological dysfunction, most commonly
due to an arterial blockage in a specific region of the brain. Stroke is a leading cause of …

Post‐stroke cognitive decline: an update and perspectives for clinical research

M Brainin, J Tuomilehto, WD Heiss… - European journal of …, 2015 - Wiley Online Library
The close relationship between stroke and dementia is an important health issue. Ischaemic
stroke can facilitate the onset of vascular dementia as well as aggravate pre‐existing …

Longitudinal effect of stroke on cognition: a systematic review

EYH Tang, O Amiesimaka, SL Harrison… - Journal of the …, 2018 - Am Heart Assoc
Background Stroke is associated with an increased risk of dementia; however, the impact of
stroke on cognition has been found to be variable, such that stroke survivors can show …

Inflammation, autoimmunity, infection, and stroke: epidemiology and lessons from therapeutic intervention

NS Parikh, AE Merkler, C Iadecola - Stroke, 2020 - Am Heart Assoc
712 Stroke March 2020 outcome of stroke. 27, 28 Rosuvastatin reduced stroke risk in
subjects who either achieved LDL-C levels of< 70 mg/dL or hs-CRP levels of< 2 mg/L …

A review and hypothesized model of the mechanisms that underpin the relationship between inflammation and cognition in the elderly

M Tangestani Fard, C Stough - Frontiers in aging neuroscience, 2019 - frontiersin.org
Age is associated with increased risk for several disorders including dementias,
cardiovascular disease, atherosclerosis, obesity, and diabetes. Age is also associated with …

Ischemic stroke outcome: A review of the influence of post-stroke complications within the different scenarios of stroke care

A Bustamante, T Garcia-Berrocoso, N Rodriguez… - European journal of …, 2016 - Elsevier
Stroke remains one of the main causes of death and disability worldwide. The challenge of
predicting stroke outcome has been traditionally assessed from a general point of view …