Longer human lives have led to a global burden of late-life disease. However, some older
people experience little ill health, a trait that should be extended to the general population …

Abstract Background Normalization Process Theory (NPT) identifies, characterises and
explains key mechanisms that promote and inhibit the implementation, embedding and …

Objective To examine the effect of optimising drug treatment on drug related hospital
admissions in older adults with multimorbidity and polypharmacy admitted to hospital …

Background The escalating use of prescribed drugs has increasingly raised concerns about
polypharmacy. This study aims to examine changes in rates of polypharmacy and potentially …

Background Little is known about the epidemiology of medication errors and medication-
related harm following transition from secondary to primary care. This systematic review …

The International Conference on Harmonization considers older people a 'special
population', as they differ from younger adults in terms of comorbidity, polypharmacy …

Adverse drug reactions (ADRs) are common in older adults, with falls, orthostatic
hypotension, delirium, renal failure, gastrointestinal and intracranial bleeding being amongst …

Background Adverse drug events are important preventable causes of hospitalization in
older adults. However, nationally representative data on adverse drug events that result in …

Background Non-steroidal anti-inflammatory drugs (NSAIDs) are a common cause of
adverse drug events (ADEs), but renal risks of NSAIDs are less well quantified than …

Adverse drug reactions (ADRs) are unwanted drug effects that have considerable economic
as well as clinical costs as they often lead to hospital admission, prolongation of hospital …