Changes in the composition of cardiac tissue develop in hypertensive patients with left
ventricular hypertrophy (ie, hypertensive heart disease) and lead to structural remodeling of …

Abstract Changes in the composition of cardiac tissue develop in arterial hypertension and
lead to structural remodeling of the myocardium. Structural remodeling is the consequence …

The early and long-term effects of coronary artery ligation on the plasma and left ventricular
angiotensin-converting enzyme (ACE and ACE2) activities, ACE and ACE2 mRNA levels …

Background: Little is known about the biological effects of angiotensin-(1–9), but available
evidence shows that angiotensin-(1–9) has beneficial effects in preventing/ameliorating …

Cardiac fibroblasts (CF) not only modulate extracellular matrix (ECM) proteins homeostasis,
but also respond to chemical and mechanical signals. CF express a variety of receptors …

Cardiac fibrosis, an important pathological feature of structural remodeling, contributes to
ventricular stiffness, diastolic dysfunction, arrhythmia and may even lead to sudden death …

Abstract Angiotensin-(19), a peptide of the non-classical renin angiotensin system, has been
shown to prevent and revert hypertension and cardiac hypertrophy. We hypothetized that …

Background Angiotensin‐converting enzyme 2 (ACE2) is a homologue of angiotensin‐
converting enzyme (ACE) and produces angiotensin peptides (APs), such as angiotensin 1 …

We wished to elucidate a potential role of the tumor necrosis factor-like weak inducer of
apoptosis (TWEAK)/fibroblast growth factor-inducible molecule 14 (Fn14) axis in myocardial …

The prevalence and economic burden of atrial fibrillation (AF) are predicted to more than
double over the next few decades. In addition to anticoagulation and treatment of …