Importance Stroke is the fifth leading cause of death and a leading cause of disability in the
United States, affecting nearly 800 000 individuals annually. Observations Sudden …

Background Ischemic stroke is the leading cause of disability and one of the leading causes
of death. Ischemic stroke mimics (SMs) can account for a noteble number of diagnosed …

Rationale: Currently, there are no blood-based biomarkers with clinical utility for acute
ischemic stroke (IS). MicroRNAs show promise as disease markers because of their cell type …

Objective To explore the utility of serum neurofilament light chain (NfL) as a biomarker for
primary and secondary neuroaxonal injury after ischemic stroke (IS) and study its value for …

Computed tomography (CT) has had a profound effect on the practice of medicine. Both the
spectrum of clinical applications and the role that CT has played in enhancing the depth of …

Purpose To perform a large-scale systematic comparison of the accuracy of all commonly
used perfusion computed tomography (CT) data postprocessing methods in the definition of …

Figure 1. Matched and Mismatched perfusion computed tomography (PCT) imaging in a
patient with middle cerebral artery (MCA) occlusions. Noncontrast head CT (NCCT) and …

Cerebral perfusion x-ray computed tomography (PCT) imaging, which detects and
characterizes the ischemic penumbra, and assesses blood–brain barrier permeability with …

Amongst the most common causes of death globally, stroke is one of top three affecting over
100 million people worldwide annually. There are two classes of stroke, namely ischemic …

Background and objective CT perfusion (CTP) is rapid and accessible for emergency
ischaemic stroke diagnosis. The feasibility of introducing CTP and diagnostic accuracy …