Breast cancer has become a serious threat to women's health. Cancer progression is mainly
derived from resistance to apoptosis induced by procedures or therapies. Therefore, new …

Recent insights into the molecular and cellular mechanisms underlying cancer development
have revealed the tumor microenvironment (TME) immune cells to functionally affect the …

Bone cancer pain (BCP) is a clinically intractable mixed pain, involving inflammation and
neuropathic pain, and its mechanisms remain unclear. CXC chemokine receptor 1 (CXCR1 …

Introduction Bone cancer pain is characterized by persistent pain, usually requiring drugs to
relieve pain. Baicalin, a flavonoid compound extracted from Scutellaria baicalensis, which …

Curcumin has several pharmacological properties such as anti-inflammatory, antioxidant,
and neuroprotective activities. B14 is a curcumin analogue and is considered to be a more …

Cancer-induced bone pain (CIBP) is a type of ongoing or breakthrough pain caused by a
primary bone tumor or bone metastasis. CIBP constitutes a specific pain state with distinct …

Signal transducer and activator of transcription (STAT) signaling pathway, connected
upstream with Janus kinases (JAK) proteins, is known to be capable of the integration of …

Objective To screen the key genes of chronic pain and provide a reference for the treatment
of chronic pain. Methods We performed comprehensive bioinformatics analysis by screening …