Resolvin D1: A key endogenous inhibitor of neuroinflammation

A Roohbakhsh, L Etemad, G Karimi - Biofactors, 2022 - Wiley Online Library
After the initiation of inflammation, a series of processes start to resolve the inflammation. A
group of endogenous lipid mediators, namely specialized pro‐resolving lipid mediators is at …

The role of formyl peptide receptors in neurological diseases via regulating inflammation

J Zhu, L Li, J Ding, J Huang, A Shao… - Frontiers in Cellular …, 2021 - frontiersin.org
Formyl peptide receptors (FPRs) are a group of G protein-coupled cell surface receptors that
play important roles in host defense and inflammation. Owing to the ubiquitous expression of …

[HTML][HTML] Phospholipase A2 enzymes represent a shared pathogenic pathway in psoriasis and pityriasis rubra pilaris

S Shao, J Chen, WR Swindell, LC Tsoi, X Xing, F Ma… - JCI insight, 2021 - ncbi.nlm.nih.gov
Altered epidermal differentiation along with increased keratinocyte proliferation is a
characteristic feature of psoriasis and pityriasis rubra pilaris (PRP). However, despite this …

Isoliquiritigenin mitigates oxidative damage after subarachnoid hemorrhage in vivo and in vitro by regulating Nrf2-dependent Signaling Pathway via Targeting of …

JQ Liu, XT Zhao, FY Qin, JW Zhou, F Ding, G Zhou… - Phytomedicine, 2022 - Elsevier
Background Oxidative stress is a crucial factor leading to subarachnoid hemorrhage (SAH)-
induced early brain injury (EBI). Isoliquiritigenin has been verified as a powerful anti-oxidant …

[HTML][HTML] Hydrogen inhalation therapy regulates lactic acid metabolism following subarachnoid hemorrhage through the HIF-1α pathway

Z Peng, XJ Li, C Pang, JT Zhang, Q Zhu, JQ Sun… - Biochemical and …, 2023 - Elsevier
The neuroprotective effects of hydrogen have been demonstrated, but the mechanism is still
poorly understood. In a clinical trial of inhaled hydrogen in patients with subarachnoid …

LDC7559 inhibits microglial activation and GSDMD-dependent pyroptosis after subarachnoid hemorrhage

W Cai, Z Wu, J Lai, J Yao, Y Zeng, Z Fang… - Frontiers in …, 2023 - frontiersin.org
Mounting evidence indicates that inhibition of microglial activation and neuronal pyroptosis
plays important roles in brain function recovery after subarachnoid hemorrhage (SAH) …

Effect of chlorogenic acid via upregulating resolvin D1 inhibiting the NF-κB pathway on chronic restraint stress-induced liver inflammation

H Wang, Y Zhao, Y Zhang, T Yang, S Zhao… - Journal of Agricultural …, 2022 - ACS Publications
Chronic stress can cause chronic inflammatory injury to the liver. Chlorogenic acid (CGA) is
known to have a wide range of biological activities and anti-inflammatory effects. Resolvin …

[HTML][HTML] The role of Resolvin D1 in liver diseases

M Yang, XQ Song, M Han, H Liu - Prostaglandins & Other Lipid Mediators, 2022 - Elsevier
The liver is a parenchymatous organ closely related to immunity, detoxification and
metabolism of the three major nutrients. The inflammatory response is a protective …

Resolvins lipid mediators: potential therapeutic targets in Alzheimer and Parkinson disease

S Anand, MA Ansari, SK Sukrutha, MN Alomary… - Neuroscience, 2022 - Elsevier
Inflammation and resolution are highly programmed processes involving a plethora of
immune cells. Lipid mediators synthesized from arachidonic acid metabolism play a pivotal …

Activation of Sirtuin‐1 by Pinocembrin Treatment Contributes to Reduced Early Brain Injury after Subarachnoid Hemorrhage

Y Zeng, Z Fang, J Lai, Z Wu, W Lin… - Oxidative medicine …, 2022 - Wiley Online Library
Subarachnoid hemorrhage (SAH) as a devastating neurological disorder is closely related
to heightened oxidative insults and neuroinflammatory injury. Pinocembrin, a bioflavonoid …