Interactions between Borrelia burgdorferi and ticks

C Kurokawa, GE Lynn, JHF Pedra, U Pal… - Nature Reviews …, 2020 - nature.com
Borrelia burgdorferi is the causative agent of Lyme disease and is transmitted to vertebrate
hosts by Ixodes spp. ticks. The spirochaete relies heavily on its arthropod host for basic …

Recent progress in Lyme disease and remaining challenges

JR Bobe, BL Jutras, EJ Horn, ME Embers… - Frontiers in …, 2021 - frontiersin.org
Lyme disease (also known as Lyme borreliosis) is the most common vector-borne disease in
the United States with an estimated 476,000 cases per year. While historically, the long-term …

Not all animals need a microbiome

TJ Hammer, JG Sanders, N Fierer - FEMS microbiology letters, 2019 - academic.oup.com
It is often taken for granted that all animals host and depend upon a microbiome, yet this has
only been shown for a small proportion of species. We propose that animals span a …

Microbiota perturbation by anti-microbiota vaccine reduces the colonization of Borrelia afzelii in Ixodes ricinus

A Wu-Chuang, L Mateos-Hernandez, A Maitre… - Microbiome, 2023 - Springer
Background Ticks can transmit a broad variety of pathogens of medical importance,
including Borrelia afzelii, the causative agent of Lyme borreliosis in Europe. Tick microbiota …

Tick immune system: what is known, the interconnections, the gaps, and the challenges

AC Fogaça, G Sousa, DB Pavanelo, E Esteves… - Frontiers in …, 2021 - frontiersin.org
Ticks are ectoparasitic arthropods that necessarily feed on the blood of their vertebrate
hosts. The success of blood acquisition depends on the pharmacological properties of tick …

Grappling with the tick microbiome

S Narasimhan, A Swei, S Abouneameh, U Pal… - Trends in …, 2021 - cell.com
Ixodes scapularis and Ixodes pacificus are the predominant vectors of multiple human
pathogens, including Borrelia burgdorferi, one of the causative agents of Lyme disease in …

Update on the intricate tango between tick microbiomes and tick‐borne pathogens

SI Bonnet, T Pollet - Parasite immunology, 2021 - Wiley Online Library
The recent development of high‐throughput NGS technologies,(ie, next‐generation
sequencing) has highlighted the complexity of tick microbial communities—which include …

[HTML][HTML] Current debates and advances in tick microbiome research

A Wu-Chuang, A Hodžić, L Mateos-Hernández… - Current research in …, 2021 - Elsevier
The main importance of ticks resides in their ability to harbor pathogens that can be
transmitted to terrestrial vertebrates including humans. Recently, studies have focused on …

Polymicrobial nature of tick-borne diseases

S Sanchez-Vicente, T Tagliafierro, JL Coleman… - MBio, 2019 - Am Soc Microbiol
Tick-borne diseases have doubled in the last 12 years, and their geographic distribution has
spread as well. The clinical spectrum of tick-borne diseases can range from asymptomatic to …

Surface sterilization methods impact measures of internal microbial diversity in ticks

F Binetruy, M Dupraz, M Buysse, O Duron - Parasites & vectors, 2019 - Springer
Background Ticks are obligate blood feeders transmitting major pathogens worldwide. Over
the past few years, considerable research efforts have focused on the diversity, distribution …