Recent advances in cryo-electron microscopy have marked only the beginning of the
potential of this technique. To bring structure into cell biology, the modality of cryo-electron …

Structural biology studies inside cells and tissues require methods to thin vitrified specimens
to electron transparency. Until now, focused ion beams based on gallium have been used …

The structure, chemistry, and charge of interfaces between materials and aqueous fluids
play a central role in determining properties and performance of numerous water systems …

The spatial distribution of proteins and their arrangement within the cellular ultrastructure
regulates the opening of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) …

The relationship between sample thickness and quality of data obtained is investigated by
microcrystal electron diffraction (MicroED). Several electron microscopy (EM) grids …

When an ionic crystal dissolves in solvent, the positive and negative ions associated with
solvent molecules release from the crystal. However, the existing form, interaction, and …

Liquid-phase transmission electron microscopy (LPTEM) offers label-free imaging of
nanoparticle (NP) processes in liquid with sub-nanometer spatial and millisecond temporal …

Utilizing ionizing radiation for in situ studies in liquid media enables unique insights into
nanostructure formation dynamics. As radiolysis interferes with observations, kinetic …

A generally accepted understanding of the anomalous properties of water will only emerge if
it becomes possible to systematically characterize water in the deeply supercooled regime …

Advanced in situ techniques based on electrons and X-rays are increasingly used to gain
insights into fundamental processes in liquids. However, probing liquid samples with …