Liver sinusoidal endothelial cells (LSECs) form the wall of the hepatic sinusoids. Unlike
other capillaries, they lack an organized basement membrane and have cytoplasm that is …

Ischemia/reperfusion injury (IRI) permeates a variety of diseases and is a ubiquitous
concern in every transplantation proceeding, from whole organs to modest grafts. Given its …

Chronic liver diseases, characterized by an excessive accumulation of extracellular matrix
(ECM) resulting in scar tissue formation, are a growing health problem causing increasing …

Liver fibrosis is a common feature of sustained liver injury and represents a major public
health problem worldwide. Fibrosis is an active research field and discoveries in the last …

LSECs are a unique population of endothelial cells within the liver and are recognized as
key regulators of liver homeostasis. LSECs also play a key role in liver disease, as …

Hepatic ischemia‐reperfusion injury (IRI), in which an insufficient oxygen supply followed by
reperfusion leads to an inflammatory network and oxidative stress in disease tissue to cause …

Liver fibrosis is the common consequence of various chronic liver injuries and is mainly
characterized by the imbalance between the production and degradation of extracellular …

The mitogen-activated protein kinase signaling pathway can be activated by a variety of
growth factors, cytokines, and hormones, and mediates numerous intracellular signals …

Hepatic ischemia‐reperfusion (IR) injury is the leading cause of liver dysfunction and failure
after liver resection or transplantation and lacks effective therapeutic strategies. Here, we …

Circulating tumor cells (CTCs) are cancer cells that detach from the primary tumor and enter
the bloodstream, where they can seed new metastatic lesions in distant organs. CTCs are …