[HTML][HTML] Role of gut microbiota in type 2 diabetes pathophysiology

M Gurung, Z Li, H You, R Rodrigues, DB Jump… - …, 2020 - thelancet.com
A substantial body of literature has provided evidence for the role of gut microbiota in
metabolic diseases including type 2 diabetes. However, reports vary regarding the …

Effects of metformin on the gut microbiota in obesity and type 2 diabetes mellitus

Q Zhang, N Hu - Diabetes, Metabolic Syndrome and Obesity, 2020 - Taylor & Francis
Metformin is a first-line treatment for type 2 diabetes mellitus (T2DM); however, its underlying
mechanism is not fully understood. Gut microbiota affect the development and progression …

Health improvements of type 2 diabetic patients through diet and diet plus fecal microbiota transplantation

L Su, Z Hong, T Zhou, Y Jian, M Xu, X Zhang, X Zhu… - Scientific reports, 2022 - nature.com
Abstract Type 2 diabetes (T2D) is a major public health problem, and gut microbiota
dysbiosis has been implicated in the emergence of T2D in humans. Dietary interventions …

[HTML][HTML] Mining microbes for mental health: determining the role of microbial metabolic pathways in human brain health and disease

S Spichak, TFS Bastiaanssen, K Berding… - Neuroscience & …, 2021 - Elsevier
There is increasing knowledge regarding the role of the microbiome in modulating brain and
behaviour. Indeed, the actions of microbial metabolites are key for appropriate gut-brain …

[HTML][HTML] Interactions between NSAIDs, opioids and the gut microbiota-future perspectives in the management of inflammation and pain

ZS Zádori, K Király, M Al-Khrasani, K Gyires - Pharmacology & Therapeutics, 2023 - Elsevier
The composition of intestinal microbiota is influenced by a number of factors, including
medications, which may have a substantial impact on host physiology. Nonsteroidal anti …

A potential role for the gut microbiome in substance use disorders

KR Meckel, DD Kiraly - Psychopharmacology, 2019 - Springer
Pathological substance use disorders represent a major public health crisis with limited
effective treatment options. While much work has been done to understand the neuronal …

Effects of metformin on the gut microbiota: A systematic review

P Petakh, I Kamyshna, A Kamyshnyi - Molecular Metabolism, 2023 - Elsevier
Background The gut microbiota is increasingly recognized as a crucial factor in human
health and disease. Metformin, a commonly prescribed medication for type 2 diabetes, has …

Metabolic effects of oxytocin

SE McCormack, JE Blevins, EA Lawson - Endocrine reviews, 2020 - academic.oup.com
There is growing evidence that oxytocin (OXT), a hypothalamic hormone well recognized for
its effects in inducing parturition and lactation, has important metabolic effects in both sexes …

Metformin and gut microbiota: their interactions and their impact on diabetes

NG Vallianou, T Stratigou, S Tsagarakis - Hormones, 2019 - Springer
The ratio of human to bacterial cells in the human body (microbiota) is around 1: 1. As a
result of co-evolution of the host mucosal immune system and the microbiota, both have …

Multi-omics analysis revealing the interplay between gut microbiome and the host following opioid use

U Kolli, R Jalodia, S Moidunny, PK Singh, Y Ban… - Gut …, 2023 - Taylor & Francis
Opioid crisis is an ongoing epidemic since the past several decades in the United States.
Opioid use-associated microbial dysbiosis is emerging as a key regulator of intestinal …