W Pettersson-Yeo, P Allen, S Benetti, P McGuire… - Neuroscience & …, 2011 - Elsevier
The disconnection hypothesis suggests that the core symptoms of schizophrenia (SZ) are related to aberrant, or 'dys-', connectivity between distinct brain regions. A proliferation of …
In patients with schizophrenia neuroimaging studies have revealed global differences with some brain regions showing focal abnormalities. Examining neurocircuitry, diffusion …
Several lines of evidence suggest that the normal integration of cerebral communication may be compromised in schizophrenia, with white matter (WM) abnormalities being integral …
Background Psychotic disorders are associated with widespread reductions in white matter (WM) integrity. However, the stage at which these abnormalities first appear and whether …
BACKGROUND: White matter microstructural disruptions have been observed in patients with schizophrenia. However, whether changes exist prior to disease onset or in high-risk …
Background: Ultra-high risk (UHR) for psychosis has been associated with widespread structural brain changes in young adults. The onset of these changes and their subsequent …
E Canu, F Agosta, M Filippi - Schizophrenia research, 2015 - Elsevier
Schizophrenia has long been hypothesized to result from a disconnection syndrome due to a disruption of the association fibers of the brain. However, only with the advent of in vivo …
Disrupted thalamo-cortical connectivity is regarded as a core psychopathology in patients diagnosed with schizophrenia. However, whether the thalamo-cortical white matter …
OJN Bloemen, MB de Koning, N Schmitz… - Psychological …, 2010 - cambridge.org
BackgroundSubjects at 'ultra high risk'(UHR) for developing psychosis have differences in white matter (WM) compared with healthy controls. WM integrity has not yet been …