Association of Bone Disorder and Gene Polymorphism of PPAR-γ Pro12 Ala in Egyptian Children with β-Thalassemia

AMA Hamied, HM Ahmed, DH Eldahshan… - Thalassemia …, 2023 - mdpi.com
β-thalassemia is a genetic disorder affecting chromosome 16, inherited from one or both
parents. In spite of the improved treatment of the hematological disorder and its …

Bone health in pediatric transfusion‐dependent beta‐thalassemia: Circulating osteoprotegerin and RANKL system

I Youssry, N Saad, M Madboly, RM Samy… - Pediatric Blood & …, 2022 - Wiley Online Library
Introduction While the mechanism of bone disease in thalassemia is multifactorial and still
under investigation, the receptor activator of nuclear factor kappa B (RANK), receptor …

PPARγ Pro12Ala and C161T polymorphisms, but not PPARα L162V, are associated with osteoporosis risk in Turkish postmenopausal women

ÖK Şirin, HY Aydoğan, M Uyar, A Can - İstanbul Journal of …, 2019 - dergipark.org.tr
Stimulation of peroxisome proliferator-activated receptors (PPARs) causes mesenchymal
stem cells of the human bone marrow differentiate into adipocytes instead of osteoblasts …

Probing the single nucleotide polymorphism (Snp) of swine PPAR delta gene.

WY Liu - 2013 - cabidigitallibrary.org
Recently, it was reported that PPAR delta (PPARδ, alias PPARβ) serves as a key nuclear
transcription factor regulating the expression of myriad genes in placent nutrient absorption …

Preliminary Report on the Frequency of Pro12Ala Polymorphism of the Peroxisome Proliferator-Activated Receptor-gamma Gene in Egyptian β-Thalassemia Major …

M El-Dafrawy, N Hamed, O Ghallab… - … Blood Research & …, 2016 - journal.251news.co.in
Osteoporosis represents an important cause of morbidity in adult thalassemic patients.
Peroxisome proliferator-activated receptor-γ (PPAR γ) is a master transcriptional regulator …

[引用][C] Association of Bone Disorder and Gene Polymorphism of PPAR-γ Pro12 Ala in Egyptian Children with β-Thalassemia. Thalass. Rep. 2023, 13, 230–240

AMA Hamied, HM Ahmed, DH Eldahshan, DS Morgan… - 2023