Lung cancer staging and prognosis

GA Woodard, KD Jones, DM Jablons - Lung cancer: treatment and …, 2016 - Springer
The seventh edition of the non-small cell lung cancer (NSCLC) TNM staging system was
developed by the International Association for the Staging of Lung Cancer (IASLC) Lung …

Adjuvant systemic therapy and adjuvant radiation therapy for stage I to IIIA completely resected non–small-cell lung cancers: American Society of Clinical Oncology …

MG Kris, LE Gaspar, JE Chaft, EB Kennedy… - Journal of Clinical …, 2017 - ascopubs.org
Purpose The panel updated the American Society of Clinical Oncology (ASCO) adjuvant
therapy guideline for resected non–small-cell lung cancers. Methods ASCO convened an …

Co-occurring Genomic Alterations Define Major Subsets of KRAS-Mutant Lung Adenocarcinoma with Distinct Biology, Immune Profiles, and Therapeutic …

F Skoulidis, LA Byers, L Diao, VA Papadimitrakopoulou… - Cancer discovery, 2015 - AACR
The molecular underpinnings that drive the heterogeneity of KRAS-mutant lung
adenocarcinoma are poorly characterized. We performed an integrative analysis of …

Development and validation of an individualized immune prognostic signature in early-stage nonsquamous non–small cell lung cancer

B Li, Y Cui, M Diehn, R Li - JAMA oncology, 2017 - jamanetwork.com
Importance The prevalence of early-stage non–small cell lung cancer (NSCLC) is expected
to increase with recent implementation of annual screening programs. Reliable prognostic …

Online survival analysis software to assess the prognostic value of biomarkers using transcriptomic data in non-small-cell lung cancer

B Győrffy, P Surowiak, J Budczies, A Lánczky - PloS one, 2013 - journals.plos.org
In the last decade, optimized treatment for non-small cell lung cancer had lead to improved
prognosis, but the overall survival is still very short. To further understand the molecular …

Treatment of stage I and II non-small cell lung cancer: Diagnosis and management of lung cancer: American College of Chest Physicians evidence-based clinical …

JA Howington, MG Blum, AC Chang, AA Balekian… - Chest, 2013 - Elsevier
Background The treatment of stage I and II non-small cell lung cancer (NSCLC) in patients
with good or low surgical risk is primarily surgical resection. However, this area is …

SurvExpress: an online biomarker validation tool and database for cancer gene expression data using survival analysis

R Aguirre-Gamboa, H Gomez-Rueda… - PloS one, 2013 - journals.plos.org
Validation of multi-gene biomarkers for clinical outcomes is one of the most important issues
for cancer prognosis. An important source of information for virtual validation is the high …

The role of the tumor-microenvironment in lung cancer-metastasis and its relationship to potential therapeutic targets

SL Wood, M Pernemalm, PA Crosbie… - Cancer treatment …, 2014 - Elsevier
Non-small cell lung cancer (NSCLC) accounts for> 80% of lung cancer cases and currently
has an overall five-year survival rate of only 15%. Patients presenting with advanced stage …

Predictive gene signature in MAGE-A3 antigen-specific cancer immunotherapy

F Ulloa-Montoya, J Louahed, B Dizier… - Journal of Clinical …, 2013 - ascopubs.org
Purpose To detect a pretreatment gene expression signature (GS) predictive of response to
MAGE-A3 immunotherapeutic in patients with metastatic melanoma and to investigate its …

Development and validation of an immune‐related prognostic signature in lung adenocarcinoma

S Sun, W Guo, Z Wang, X Wang, G Zhang… - Cancer …, 2020 - Wiley Online Library
Background Lung adenocarcinomas (LUAD) is the most common histological subtype of
lung cancers. Tumor immune microenvironment (TIME) is involved in tumorigeneses …