Natural products have played a critical role in medicine due to their ability to bind and
modulate cellular targets involved in disease. Medicinal plants hold a variety of bioactive …

The discovery and advances of medicines may be considered as the ultimate relevant
translational science effort that adds to human invulnerability and happiness. But advancing …

This chapter comprehensively explores the pivotal role of artificial intelligence (AI) in drug
discovery and development, encapsulating its potentials, methodologies, real-world …

In recent years, even with remarkable scientific advancements and a significant increase of
global research and development spending, drugs are frequently withdrawn from markets …

Traditionally, most drugs have been discovered using phenotypic or target‐based screens.
Subsequently, their indications are often expanded on the basis of clinical observations …

In the era of antimicrobial resistance, the prevalence of multidrug-resistant microorganisms
that resist conventional antibiotic treatment has steadily increased. Thus, it is now …

Quantitative structure–activity relationship (QSAR) methods and related approaches have
been used to investigate the molecular features that influence the absorption, distribution …

Nanomedicine is a field of medicine that uses nanotechnology to develop new diagnostic
tools and therapies for a wide range of medical conditions. It encompasses a variety of …

Objective Computational drug repositioning can lead to a considerable reduction in cost and
time in any drug development process. Recent approaches have addressed the network …

The molecular pathways that govern human disease consist of molecular circuits that
coalesce into complex, overlapping networks. These network pathways are presumably …