The development of the mammalian cerebellum is orchestrated by both cell-autonomous
programs and inductive environmental influences. Here, we describe the main processes of …

There has been significant advancement in various aspects of scientific knowledge
concerning the role of cerebellum in the etiopathogenesis of autism. In the current …

The adult mammalian cerebellar cortex is generally assumed to have a uniform
cytoarchitecture. Differences in cerebellar function are thought to arise primarily through …

Caspase-3, onto which there is a convergence of the intrinsic and extrinsic apoptotic
pathways, is the main executioner of apoptosis. We here review the current literature on the …

Granule cells (GCs) are the most numerous cell type in the cerebellum and indeed, in the
brain: at least 99% of all cerebellar neurons are granule cells. In this review article, we first …

The cerebellum has a well-established role in maintaining motor coordination and studies of
cerebellar learning suggest that it does this by recognizing neural patterns, which it uses to …

A common pathological finding in autism is a localized deficit in Purkinje cells (PCs).
Cerebellar abnormalities have also been reported in schizophrenia. Using a mouse model …

Deep brain stimulation (DBS) relieves motor dysfunction in Parkinson's disease, and other
movement disorders. Here, we demonstrate the potential benefits of DBS in a model of …

The cerebellum has a well-established role in controlling motor functions such coordination,
balance, posture, and skilled learning. There is mounting evidence that it might also play a …

Blast exposure can cause mild traumatic brain injury (TBI) in mice and other mammals.
However, there are important gaps in our understanding of the neuropathology underlying …