Heart failure with preserved ejection fraction

CE Hamo, C DeJong, N Hartshorne-Evans… - Nature Reviews …, 2024 - nature.com
Heart failure with preserved ejection fraction (HFpEF) accounts for nearly half of all heart
failure cases and has a prevalence that is expected to rise with the growing ageing …

Global epidemiology of heart failure

MS Khan, I Shahid, A Bennis, A Rakisheva… - Nature Reviews …, 2024 - nature.com
Heart failure (HF) is a heterogeneous clinical syndrome marked by substantial morbidity and
mortality. The natural history of HF is well established; however, epidemiological data are …

The role of multimorbidity in patients with heart failure across the left ventricular ejection fraction spectrum: Data from the Swedish Heart Failure Registry

D Tomasoni, C Vitale, F Guidetti… - European Journal of …, 2024 - Wiley Online Library
Aims The aim of this analysis was to provide data on the overall comorbidity burden, both
cardiovascular (CV) and non‐CV, in a large real‐world heart failure (HF) population across …

Update on obesity, the obesity paradox, and obesity management in heart failure

PL Alebna, A Mehta, A Yehya, CJ Lavie… - Progress in …, 2024 - Elsevier
Obesity is a major public health challenge worldwide. It is costly, predisposes to many
cardiovascular (CV) diseases (CVD), is increasing at an alarming rate, and …

Obesity and cardiovascular disease: an ESC clinical consensus statement

KC Koskinas, EM Van Craenenbroeck… - European Heart …, 2024 - academic.oup.com
The global prevalence of obesity has more than doubled over the past four decades,
currently affecting more than a billion individuals. Beyond its recognition as a high-risk …

[HTML][HTML] Effect of Semaglutide on Cardiac Structure and Function in Patients With Obesity-RelatedáHeartáFailure

SD Solomon, JW Ostrominski, X Wang, SJ Shah… - Journal of the American …, 2024 - Elsevier
Background Obesity is associated with adverse cardiac remodeling and is a key driver for
the development and progression of heart failure (HF). Once-weekly semaglutide (2.4 ámg) …

The challenges of assessing adiposity in a clinical setting

E Börgeson, S Tavajoh, S Lange… - Nature Reviews …, 2024 - nature.com
To tackle the burden of obesity-induced cardiometabolic disease, the scientific community
relies on accurate and reproducible adiposity measurements in the clinic. These …

Diet-induced obesity affects influenza disease severity and transmission dynamics in ferrets

V Meliopoulos, R Honce, B Livingston, V Hargest… - Science …, 2024 - science.org
Obesity, and the associated metabolic syndrome, is a risk factor for increased disease
severity with a variety of infectious agents, including influenza virus. Yet, the mechanisms …

Waist-to-height ratio for the obesity paradox in heart failure: is it a matter of fitness?

GM Lin, KZ Tsai, CJ Lavie - European heart journal, 2023 - academic.oup.com
The obesity survival paradox has been observed in patients with chronic heart failure (HF)
for longer than 20 years. 1 Body mass index (BMI), defined as the body weight (kg) divided …

[HTML][HTML] Association of Body Mass Index with outcomes in patients with heart failure with reduced ejection fraction (HFrEF)

M Czapla, S Surma, A Kwaśny, Ł Lewandowski - Nutrients, 2024 - mdpi.com
Heart failure (HF) is a major health issue, affecting up to 2% of the adult population
worldwide. Given the increasing prevalence of obesity and its association with various …