Lipid-based nanosystems: the next generation of cancer immune therapy

Z Cheng, SF Fobian, E Gurrieri, M Amin… - Journal of Hematology & …, 2024 - Springer
Immunotherapy has become an important part of the oncotherapy arsenal. Its applicability in
various cancer types is impressive, as well as its use of endogenous mechanisms to achieve …

Cancer immunotherapy and delivery system: an update

M Yang, OT Olaoba, C Zhang, ET Kimchi… - Pharmaceutics, 2022 - mdpi.com
With an understanding of immunity in the tumor microenvironment, immunotherapy turns out
to be a powerful tool in the clinic to treat many cancers. The strategies applied in cancer …

Bright future or blind alley? CAR-T cell therapy for solid tumors

K Zhang, H Chen, F Li, S Huang, F Chen… - Frontiers in …, 2023 - frontiersin.org
Chimeric antigen receptor (CAR) T cells therapy has emerged as a significant breakthrough
in adoptive immunotherapy for hematological malignancies with FDA approval. However …

Nanoparticle strategies to improve the delivery of anticancer drugs across the blood–brain barrier to treat brain tumors

WJF Vanbilloen, JS Rechberger, JB Anderson… - Pharmaceutics, 2023 - mdpi.com
Primary brain and central nervous system (CNS) tumors are a diverse group of neoplasms
that occur within the brain and spinal cord. Although significant advances in our …

Emerging applications of nanotechnology in context to immunology: A comprehensive review

H Mobeen, M Safdar, A Fatima, S Afzal… - … in Bioengineering and …, 2022 - frontiersin.org
Numerous benefits of nanotechnology are available in many scientific domains. In this
sense, nanoparticles serve as the fundamental foundation of nanotechnology. Recent …

Nanoparticle-based chimeric antigen receptor therapy for cancer immunotherapy

S Shin, P Lee, J Han, SN Kim, J Lim, DH Park… - Tissue Engineering and …, 2023 - Springer
Adoptive cell therapy with chimeric antigen receptor (CAR)-engineered T cells (CAR-Ts) has
emerged as an innovative immunotherapy for hematological cancer treatment. However, the …

Cancer immunotherapy and its facilitation by nanomedicine

C Sui, H Wu, X Li, Y Wang, J Wei, J Yu, X Wu - Biomarker Research, 2024 - Springer
Cancer immunotherapy has sparked a wave of cancer research, driven by recent successful
proof-of-concept clinical trials. However, barriers are emerging during its rapid development …

Emerging trends in nano-driven immunotherapy for treatment of cancer

G Kandasamy, Y Karuppasamy, UM Krishnan - Vaccines, 2023 - mdpi.com
Despite advancements in the development of anticancer medications and therapies, cancer
still has the greatest fatality rate due to a dismal prognosis. Traditional cancer therapies …

Biomaterials to enhance adoptive cell therapy

N Eckman, A Nejatfard, R Cavet… - Nature Reviews …, 2024 - nature.com
Adoptive cell therapy (ACT) harnesses the capabilities of immune cells to fight complex
diseases such as cancer. Treatment with adoptive transfer of engineered cells has led to …

Multimodal in vivo tracking of chimeric antigen receptor T cells in preclinical glioblastoma models

WE Wu, E Chang, L Jin, S Liu, CH Huang… - Investigative …, 2023 - journals.lww.com
Objectives Iron oxide nanoparticles have been used to track the accumulation of chimeric
antigen receptor (CAR) T cells with magnetic resonance imaging (MRI). However, the only …