[HTML][HTML] Learnings from 30 years of reported efficacy and safety of vagus nerve stimulation (VNS) for epilepsy treatment: a critical review

DH Toffa, L Touma, T El Meskine, A Bouthillier… - Seizure, 2020 - Elsevier
Three decades after its introduction as an adjuvant therapeutic option in the management of
selective drug-resistant epilepsy cases (DRE), vagus nerve stimulation (VNS) retains …

Vagus nerve stimulation in brain diseases: Therapeutic applications and biological mechanisms

Y Wang, G Zhan, Z Cai, B Jiao, Y Zhao, S Li… - … & Biobehavioral Reviews, 2021 - Elsevier
Brain diseases, including neurodegenerative, cerebrovascular and neuropsychiatric
diseases, have posed a deleterious threat to human health and brought a great burden to …

Expert opinion on diagnosis and management of epilepsy‐associated comorbidities

J Peltola, R Surges, B Voges, TJ von Oertzen - Epilepsia Open, 2024 - Wiley Online Library
Apart from seizure freedom, the presence of comorbidities related to neurological,
cardiovascular, or psychiatric disorders is the largest determinant of a reduced health …

Vagus nerve stimulation for epilepsy: A narrative review of factors predictive of response

HJ Clifford, MP Paranathala, Y Wang, RH Thomas… - …, 2024 - Wiley Online Library
Vagus nerve stimulation (VNS) is an established therapy for drug‐resistant epilepsy.
However, there is a lack of reliable predictors of VNS response in clinical use. The …

Vagus nerve stimulation for drug resistant epilepsy: clinical outcome, adverse events, and potential prognostic factors in a single center experience

M Shan, H Mao, H Xie, Y Gan, D Wu, J Song… - Journal of Clinical …, 2022 - mdpi.com
Objective: Vagus nerve stimulation (VNS) has been used for adjunctive treatment in drug
resistant epilepsy (DRE) for decades. Nevertheless, information is lacking on possible …

[HTML][HTML] Rapid titration of VNS therapy reduces time-to-response in epilepsy

M Tzadok, R Verner, L Kann, D Tungala, C Gordon… - Epilepsy & Behavior, 2022 - Elsevier
Background Common titration strategies for vagus nerve stimulation (VNS) prioritize
monitoring of tolerability during small increases in stimulation intensity over several months …

Health technology assessment report on vagus nerve stimulation in drug-resistant epilepsy

CE Marras, G Colicchio, L De Palma… - International Journal of …, 2020 - mdpi.com
Background: Vagus nerve stimulation (VNS) is a palliative treatment for medical intractable
epileptic syndromes not eligible for resective surgery. Health technology assessment (HTA) …

Efficacy and potential predictors of vagus nerve stimulation therapy in refractory postencephalitic epilepsy

S Liu, Z Xiong, J Wang, C Tang… - … in Chronic Disease, 2022 - journals.sagepub.com
Background: Vagus nerve stimulation (VNS) is a therapeutic approach for patients with
refractory postencephalitic epilepsy (PEE), which is characterized by drug resistance and …

Long-term outcomes and prognosis factors of vagus nerve stimulation in patients with refractory epilepsy

C Xu, H Lin, J Xu, X Zhang, G Hao, QQ Liu, C Ding… - Acta Epileptologica, 2022 - Springer
Background Vagus nerve stimulation (VNS) is an effective treatment for patients with
refractory epilepsy, yet with varied predictive factors and heterogeneous long-term …

Baseline characteristics and predictors for early implantation of vagus nerve stimulation therapy in people with drug‐resistant epilepsy: Observations from an …

P Kwan, M Boffini, F Fahoum, R El Tahry… - Epilepsia …, 2024 - Wiley Online Library
Objective Vagus nerve stimulation (VNS) Therapy is routinely indicated for people with drug‐
resistant epilepsy (DRE). We analyzed the baseline characteristics of individuals receiving …