Mechanisms of protein quality control in the endoplasmic reticulum by a coordinated Hsp40-Hsp70-Hsp90 system
JLM Kotler, TO Street - Annual review of biophysics, 2023 - annualreviews.org
The Hsp40, Hsp70, and Hsp90 chaperone families are ancient, highly conserved, and
critical to cellular protein homeostasis. Hsp40 chaperones can transfer their protein clients to …
critical to cellular protein homeostasis. Hsp40 chaperones can transfer their protein clients to …
Site identification by ligand competitive saturation-biologics approach for structure-based protein charge prediction
Protein-based therapeutics typically require high concentrations of the active protein, which
can lead to protein aggregation and high solution viscosity. Such solution behaviors can …
can lead to protein aggregation and high solution viscosity. Such solution behaviors can …
[PDF][PDF] J-domain Region of ERdj3 Stabilizes a Conformational Intermediate of BiP Senior Thesis
Z Luo - 2023 - scholarworks.brandeis.edu
1 J-domain Region of ERdj3 Stabilizes a Conformational Intermediate of BiP Senior Thesis
Presented to The Faculty of the School Page 1 1 J-domain Region of ERdj3 Stabilizes a …
Presented to The Faculty of the School Page 1 1 J-domain Region of ERdj3 Stabilizes a …
J-domain Region of ERdj3 Stabilizes a Conformational Intermediate of BiP
Z Luo - 2023 - scholarworks.brandeis.edu
1 J-domain Region of ERdj3 Stabilizes a Conformational Intermediate of BiP Senior Thesis
Presented to The Faculty of the School Page 1 1 J-domain Region of ERdj3 Stabilizes a …
Presented to The Faculty of the School Page 1 1 J-domain Region of ERdj3 Stabilizes a …
Structural explanation for how the BiP chaperone accelerates closure of Grp94 chaperone
L Han - scholarworks.brandeis.edu
BiP and Grp94, the endoplasmic reticulum (ER) paralogs of the highly conserved Hsp70 and
Hsp90 chaperone families, work together in client protein folding and maturation. During …
Hsp90 chaperone families, work together in client protein folding and maturation. During …