Cystic fibrosis (CF) is both the most common and most lethal genetic disease in the
Caucasian population. CF is caused by mutations in the cystic fibrosis transmembrane …

Neutrophils have a prominent role in all human immune responses against any type of
pathogen or stimulus. The lungs are a major neutrophil reservoir and neutrophilic …

Genetic defects in cystic fibrosis (CF) transmembrane conductance regulator (CFTR) gene
cause CF. Infants with CFTR mutations show a peribronchial neutrophil infiltration prior to …

Rationale: Neutrophils are recruited to the airways of individuals with cystic fibrosis (CF). In
adolescents and adults with CF, airway neutrophils actively exocytose the primary granule …

Troubling disparities in COVID-19–associated mortality emerged early, with nearly 70% of
deaths confined to Black/African American (AA) patients in some areas. However, targeted …

Cystic fibrosis (CF) is one of the most common life-limiting recessive genetic disorders in
Caucasians, caused by mutations in the cystic fibrosis transmembrane conductance …

Methionine oxidation and reduction is a common phenomenon occurring in biological
systems under both physiological and oxidative-stress conditions. The levels of methionine …

Neutrophils are often considered terminally differentiated and poised for bacterial killing. In
chronic diseases such as cystic fibrosis (CF), an unexplained paradox pits massive …

A deficiency in cystic fibrosis transmembrane conductance regulator (CFTR) function in CF
leads to chronic lung disease. CF is associated with abnormalities in fatty acids, ceramides …

Vanadium is available as a dietary supplement and also is known to be toxic if inhaled, yet
little information is available concerning the effects of vanadium on mammalian metabolism …