[HTML][HTML] New frontiers in metabolomics: from measurement to insight

E Riekeberg, R Powers - F1000Research, 2017 - ncbi.nlm.nih.gov
Metabolomics is the newest addition to the “omics” disciplines and has shown rapid growth
in its application to human health research because of fundamental advancements in …

Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women

L Hoyles, JM Fernández-Real, M Federici, M Serino… - Nature medicine, 2018 - nature.com
Hepatic steatosis is a multifactorial condition that is often observed in obese patients and is
a prelude to non-alcoholic fatty liver disease. Here, we combine shotgun sequencing of fecal …

Metaproteome and metabolome of oral microbial communities

N Bostanci, M Grant, K Bao, A Silbereisen… - Periodontology …, 2021 - Wiley Online Library
The emergence of high‐throughput technologies for the comprehensive measurement of
biomolecules, also referred to as “omics” technologies, has helped us gather “big data” and …

FELLA: an R package to enrich metabolomics data

S Picart-Armada, F Fernández-Albert, M Vinaixa… - BMC …, 2018 - Springer
Background Pathway enrichment techniques are useful for understanding experimental
metabolomics data. Their purpose is to give context to the affected metabolites in terms of …

Extensive regulation of enzyme activity by phosphorylation in Escherichia coli

E Schastnaya, Z Raguz Nakic, CH Gruber… - Nature …, 2021 - nature.com
Protein serine/threonine/tyrosine (S/T/Y) phosphorylation is an essential and frequent post-
translational modification in eukaryotes, but historically has been considered less prevalent …

Genomic attributes of airway commensal bacteria and mucosa

L Cuthbertson, U Löber, JS Ish-Horowicz… - Communications …, 2024 - nature.com
Microbial communities at the airway mucosal barrier are conserved and highly ordered, in
likelihood reflecting co-evolution with human host factors. Freed of selection to digest …

Metabolomic approaches to study chemical exposure-related metabolism alterations in mammalian cell cultures

A Balcerczyk, C Damblon, B Elena-Herrmann… - International Journal of …, 2020 - mdpi.com
Biological organisms are constantly exposed to an immense repertoire of molecules that
cover environmental or food-derived molecules and drugs, triggering a continuous flow of …

The translational regulator FMRP controls lipid and glucose metabolism in mice and humans

A Leboucher, DF Pisani, L Martinez-Gili, J Chilloux… - Molecular …, 2019 - Elsevier
Abstract Objectives The Fragile X Mental Retardation Protein (FMRP) is a widely expressed
RNA-binding protein involved in translation regulation. Since the absence of FMRP leads to …

The putatively high‐altitude adaptation of macaque monkeys: Evidence from the fecal metabolome and gut microbiome

D Li, W Xia, X Cui, M Zhao, K Huang… - Evolutionary …, 2023 - Wiley Online Library
Animals living in high‐altitude environments, such as the Tibetan Plateau, must face harsh
environmental conditions (eg, hypoxia, cold, and strong UV radiation). These animals' …

metaGraphite–a new layer of pathway annotation to get metabolite networks

G Sales, E Calura, C Romualdi - Bioinformatics, 2019 - academic.oup.com
Motivation Metabolomics is an emerging 'omics' science involving the characterization of
metabolites and metabolism in biological systems. Few bioinformatic tools have been …