Adaptive learning under expected and unexpected uncertainty

A Soltani, A Izquierdo - Nature Reviews Neuroscience, 2019 - nature.com
The outcome of a decision is often uncertain, and outcomes can vary over repeated
decisions. Whether decision outcomes should substantially affect behaviour and learning …

[HTML][HTML] The mediodorsal thalamus as a higher order thalamic relay nucleus important for learning and decision-making

AS Mitchell - Neuroscience & Biobehavioral Reviews, 2015 - Elsevier
Recent evidence from monkey models of cognition shows that the magnocellular
subdivision of the mediodorsal thalamus (MDmc) is more critical for learning new …

What does the mediodorsal thalamus do?

AS Mitchell, S Chakraborty - Frontiers in systems neuroscience, 2013 - frontiersin.org
Dense amnesia can result from damage to the medial diencephalon in humans and in
animals. In humans this damage is diffuse and can include the mediodorsal nuclei of the …

Cognitive functions and neurodevelopmental disorders involving the prefrontal cortex and mediodorsal thalamus

Z Ouhaz, H Fleming, AS Mitchell - Frontiers in neuroscience, 2018 - frontiersin.org
The mediodorsal nucleus of the thalamus (MD) has been implicated in executive functions
(such as planning, cognitive control, working memory, and decision-making) because of its …

[HTML][HTML] Combining brain perturbation and neuroimaging in non-human primates

PC Klink, JF Aubry, VP Ferrera, AS Fox… - NeuroImage, 2021 - Elsevier
Brain perturbation studies allow detailed causal inferences of behavioral and neural
processes. Because the combination of brain perturbation methods and neural …

Advances in understanding mechanisms of thalamic relays in cognition and behavior

AS Mitchell, SM Sherman, MA Sommer… - Journal of …, 2014 - Soc Neuroscience
The main impetus for a mini-symposium on corticothalamic interrelationships was the recent
number of studies highlighting the role of the thalamus in aspects of cognition beyond …

Thalamocortical interactions in cognition and disease: The mediodorsal and anterior thalamic nuclei

BAL Perry, E Lomi, AS Mitchell - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
The mediodorsal thalamus (MD) and anterior thalamic nuclei (ATN) are two adjacent brain
nodes that support our ability to make decisions, learn, update information, form and retrieve …

Disentangling the influences of multiple thalamic nuclei on prefrontal cortex and cognitive control

JM Phillips, NA Kambi, MJ Redinbaugh… - Neuroscience & …, 2021 - Elsevier
The prefrontal cortex (PFC) has a complex relationship with the thalamus, involving many
nuclei which occupy predominantly medial zones along its anterior-to-posterior extent …

Homing in on consciousness in the nervous system: An action-based synthesis

E Morsella, CA Godwin, TK Jantz… - Behavioral and Brain …, 2016 - cambridge.org
What is the primary function of consciousness in the nervous system? The answer to this
question remains enigmatic, not so much because of a lack of relevant data, but because of …

Nicotinic, glutamatergic and dopaminergic synaptic transmission and plasticity in the mesocorticolimbic system: focus on nicotine effects

F Pistillo, F Clementi, M Zoli, C Gotti - Progress in neurobiology, 2015 - Elsevier
Cigarette smoking is currently the leading cause of preventable deaths and disability
throughout the world, being responsible for about five million premature deaths/year …