Plasmids have a key role in bacterial ecology and evolution because they mobilize
accessory genes by horizontal gene transfer. However, recent studies have revealed that …

Mobile genetic elements are key to the evolution of bacteria and traits that affect host and
ecosystem health. Here, we use a framework of a hierarchical and modular system that …

Plasmid persistence in bacterial populations is strongly influenced by the fitness effects
associated with plasmid carriage. However, plasmid fitness effects in wild-type bacterial …

Plasmids play an important role in bacterial genome evolution by transferring genes
between lineages. Fitness costs associated with plasmid carriage are expected to be a …

The'plasmid paradox'arises because, although plasmids are common features of bacterial
genomes, theoretically they should not exist: rates of conjugation were believed insufficient …

Enterococcus faecalis is a commensal and nosocomial pathogen, which is also ubiquitous
in animals and insects, representing a classical generalist microorganism. Here, we study E …

Introduction Genome-based analysis is crucial in monitoring antibiotic-resistant bacteria
(ARB) and antibiotic-resistance genes (ARGs). Short-read sequencing is typically used to …

Conjugative plasmids play a key role in the dissemination of antimicrobial resistance (AMR)
genes across bacterial pathogens. AMR plasmids are widespread in clinical settings, but …

Background Resistance to third-generation cephalosporins, often mediated by extended-
spectrum beta-lactamases (ESBLs), is a considerable issue in hospital-associated infections …

Overcoming multidrug resistance mechanisms is an intricate issue to fight against
pathogenic bacterial and cancer cells wherein smart application of metal nanoparticles …