Integrin-linked kinase (ILK): the known vs. the unknown and perspectives
A Górska, AJ Mazur - Cellular and Molecular Life Sciences, 2022 - Springer
Integrin-linked kinase (ILK) is a multifunctional molecular actor in cell–matrix interactions,
cell adhesion, and anchorage-dependent cell growth. It combines functions of a signal …
cell adhesion, and anchorage-dependent cell growth. It combines functions of a signal …
Metastatic atypical and anaplastic meningioma: a case series and review of the literature
Background Atypical (World Health Organization grade II) and anaplastic (World Health
Organization grade III) meningiomas are rare, accounting for less than 5% of all …
Organization grade III) meningiomas are rare, accounting for less than 5% of all …
Proteomic analysis discovers the differential expression of novel proteins and phosphoproteins in meningioma including NEK9, HK2 and SET and deregulation of …
Background Meningioma is the most frequent primary intracranial tumour. Surgical resection
remains the main therapeutic option as pharmacological intervention is hampered by poor …
remains the main therapeutic option as pharmacological intervention is hampered by poor …
Cr (VI)-induced autophagy protects L-02 hepatocytes from apoptosis through the ROS-AKT-mTOR pathway
Q Liang, Y Xiao, K Liu, C Zhong, M Zeng… - Cellular Physiology and …, 2018 - karger.com
Abstract Background/Aims: Hexavalent chromium [Cr (VI)] pollution has become a global
concern for both ecosystems and human health. Our previous study revealed Cr (VI) could …
concern for both ecosystems and human health. Our previous study revealed Cr (VI) could …
DUSP22 suppresses tumor progression by directly dephosphorylating AKT in non‐small cell lung cancer
J Chen, G Kang, W Lei, J Li, H Wang… - Molecular …, 2024 - Wiley Online Library
Protein kinase B (AKT) plays a pivotal in regulating cell migration, proliferation, apoptosis,
and survival, making it a prominent target for anticancer therapy. While the kinase activity of …
and survival, making it a prominent target for anticancer therapy. While the kinase activity of …
Comprehending meningioma signaling cascades using multipronged proteomics approaches & targeted validation of potential markers
Meningiomas are one of the most prevalent primary brain tumors. Our study aims to obtain
mechanistic insights of meningioma pathobiology using mass spectrometry-based label-free …
mechanistic insights of meningioma pathobiology using mass spectrometry-based label-free …
ILK inhibition reduces osteophyte formation through suppression of osteogenesis in BMSCs via Akt/GSK-3β/β-catenin pathway
Z Huang, L Huang, J Ding, Y Huang, X Huang… - Molecular Biology …, 2024 - Springer
Background Osteophyte development is a common characteristic of inflammatory skeletal
diseases. Elevated osteogenic differentiation of bone marrow mesenchymal stem cells …
diseases. Elevated osteogenic differentiation of bone marrow mesenchymal stem cells …
MiR-205 inhibits sporadic vestibular schwannoma cell proliferation by targeting cyclin-dependent kinase 14
X Yin, Z Huo, S Yan, Z Wang, T Yang, H Wu, Z Zhang - World Neurosurgery, 2021 - Elsevier
Background Sporadic vestibular schwannoma (VS) is a benign primary tumor that arises
from the vestibular nerve. Growing VS can negatively compress the brain stem, which can …
from the vestibular nerve. Growing VS can negatively compress the brain stem, which can …
[PDF][PDF] ILK/AKT signaling regulates miR-21 expression in vestibular Schwannoma and Meningioma
M Mercado-Pimentel, N Ly, B Smith, C Retana… - Austin J. Med …, 2018 - researchgate.net
Hypothesis: Inhibition of the ILK/AKT pathway with OSU-T315 decreases miR-21 releasing
the repression of miR-21 targets in vestibular schwannoma (VS) and meningioma …
the repression of miR-21 targets in vestibular schwannoma (VS) and meningioma …