Natural Products Derived from Marine Sponges with Antitumor Potential against Lung Cancer: A Systematic Review
A Ortigosa-Palomo, F Quiñonero, R Ortiz, F Sarabia… - Marine Drugs, 2024 - mdpi.com
Non-small-cell lung cancer (NSCLC), the most commonly diagnosed cancer and the leading
cause of cancer-related death worldwide, has been extensively investigated in the last …
cause of cancer-related death worldwide, has been extensively investigated in the last …
Callyspongia spp.: Secondary Metabolites, Pharmacological Activities, and Mechanisms
YE Hadisaputri, AA Nurhaniefah, S Sukmara… - Metabolites, 2023 - mdpi.com
One of the most widespread biotas in the sea is the sponge. Callyspongia is a sponge
genus found in the seas, making it easily available. In this review, the pharmacological …
genus found in the seas, making it easily available. In this review, the pharmacological …
Study of the PI3K/Akt/mTOR signaling pathway in vitro and molecular docking analysis of periplocin inhibits cell cycle progression and induces apoptosis in MDA‐MB …
X Liu, J Liu, B Yan, Z Quan, X Wang… - Environmental …, 2024 - Wiley Online Library
Breast cancer mainly affects women and is the second leading cause of cancer‐related
deaths worldwide. Breast cancer affects women aged 15–59. The current study explored …
deaths worldwide. Breast cancer affects women aged 15–59. The current study explored …
Anticancer property and normal cell toxicity profile of pyrrolidine‐based platinum (II) complexes: Their DNA, BSA interaction, and molecular docking
The bioactivity and cytotoxic property of cis‐[Pt (AEP) Cl2](C‐1);[Pt (AEP)(OH2) 2](NO3) 2 (C‐
2);[Pt (AEP)(GSH)(C‐3)]; and [Pt (AEP)(DL‐meth)] 2+(C‐4)(where AEP= 1‐[2‐Aminoethyl] …
2);[Pt (AEP)(GSH)(C‐3)]; and [Pt (AEP)(DL‐meth)] 2+(C‐4)(where AEP= 1‐[2‐Aminoethyl] …
G-4 inhibits triple negative breast cancer by inducing cell apoptosis and promoting LCN2-dependent ferroptosis
G Sun, J Wang, F Liu, C Zhao, S Cui, Z Wang… - Biochemical …, 2024 - Elsevier
Compound G-4 is a derivate of cyclin-dependent kinase inhibitor Rocovitine and showed
strong sensitivity to triple negative breast cancer (TNBC) cells. In this study, the antitumor …
strong sensitivity to triple negative breast cancer (TNBC) cells. In this study, the antitumor …
The Effect of G. applanatum Crude Polysaccharide Extract on Proinflammatory Cytokines and Proapoptotic Caspases in HeLa Cell Line: An In Vitro Study
Q A'yun, RJK Susilo, S Hayaza… - Advances in …, 2023 - Wiley Online Library
Polysaccharide extracts exhibit promise as potential anticancer agents. Among the fungi rich
in polysaccharide content, G. applanatum stands out; however, its anticancer activity …
in polysaccharide content, G. applanatum stands out; however, its anticancer activity …
Gallic acid suppresses the progression of triple-negative breast cancer HCC1806 cells via modulating PI3K/AKT/EGFR and MAPK signaling pathways
S Lin, HZ Qin, ZY Li, H Zhu, L Long… - Frontiers in Pharmacology, 2022 - frontiersin.org
Triple-negative breast cancer (TNBC) is a severe threat to women's health because of its
aggressive nature, early age of onset, and high recurrence rate. Therefore, in this study, we …
aggressive nature, early age of onset, and high recurrence rate. Therefore, in this study, we …
Antiproliferative effect of indeno [1, 2-d] thiazolo [3, 2-a] pyrimidine analogues on IL-6 mediated STAT3 and role of the apoptotic pathway in albino Wistar rats of ethyl …
Lung cancer (LC) ranks second most prevalent cancer in females after breast cancer and
second in males after prostate cancer. Based on the GLOBOCAN 2020 report, India …
second in males after prostate cancer. Based on the GLOBOCAN 2020 report, India …
Antiproliferative, apoptotic and anti-inflammatory potential of 5H-benzo [h] thiazolo [2, 3-b] quinazoline analogues: Novel series of anticancer compounds
Lung cancer (LC) is the most common cancer in males. As per GLOBOCAN 2020, 8.1% of
deaths and 5.9% of cases of LC were reported in India. Our laboratory has previously …
deaths and 5.9% of cases of LC were reported in India. Our laboratory has previously …
The alpha2-adrenergic receptor agonist clonidine protects against cerebral ischemia/reperfusion induced neuronal apoptosis in rats
Z He, BK Yin, K Wang, B Zhao, Y Chen, ZC Li… - Metabolic Brain …, 2024 - Springer
Apoptosis is the crucial pathological mechanism following cerebral ischemic injury. Our
previous studies demonstrated that clonidine, one agonist of alpha2-adrenergic receptor (α2 …
previous studies demonstrated that clonidine, one agonist of alpha2-adrenergic receptor (α2 …