Mechanisms governing activity-dependent synaptic pruning in the developing mammalian CNS
TE Faust, G Gunner, DP Schafer - Nature Reviews Neuroscience, 2021 - nature.com
Almost 60 years have passed since the initial discovery by Hubel and Wiesel that changes
in neuronal activity can elicit developmental rewiring of the central nervous system (CNS) …
in neuronal activity can elicit developmental rewiring of the central nervous system (CNS) …
Neurodevelopmental optimization after early-life adversity: cross-species studies to elucidate sensitive periods and brain mechanisms to inform early intervention
Human brain development is influenced by early-life experiences, particularly during
sensitive periods, with impact on cognitive and emotional outcomes. Understanding how the …
sensitive periods, with impact on cognitive and emotional outcomes. Understanding how the …
Early stress-induced impaired microglial pruning of excitatory synapses on immature CRH-expressing neurons provokes aberrant adult stress responses
Several mental illnesses, characterized by aberrant stress reactivity, often arise after early-
life adversity (ELA). However, it is unclear how ELA affects stress-related brain circuit …
life adversity (ELA). However, it is unclear how ELA affects stress-related brain circuit …
Limited functional convergence of eye-specific inputs in the retinogeniculate pathway of the mouse
Segregation of retinal ganglion cell (RGC) axons by type and eye of origin is considered a
hallmark of dorsal lateral geniculate nucleus (dLGN) structure. However, recent anatomical …
hallmark of dorsal lateral geniculate nucleus (dLGN) structure. However, recent anatomical …
Short-term plasticity in the human visual thalamus
While there is evidence that the visual cortex retains a potential for plasticity in adulthood,
less is known about the subcortical stages of visual processing. Here, we asked whether …
less is known about the subcortical stages of visual processing. Here, we asked whether …
Widespread and multifaceted binocular integration in the mouse primary visual cortex
The brain combines two-dimensional images received from the two eyes to form a percept of
three-dimensional surroundings. This process of binocular integration in the primary visual …
three-dimensional surroundings. This process of binocular integration in the primary visual …
Human deprivation amblyopia: treatment insights from animal models
Amblyopia is a common visual impairment that develops during the early years of postnatal
life. It emerges as a sequela to eye misalignment, an imbalanced refractive state, or …
life. It emerges as a sequela to eye misalignment, an imbalanced refractive state, or …
Mechanisms of plasticity in subcortical visual areas
M Duménieu, B Marquèze-Pouey, M Russier… - Cells, 2021 - mdpi.com
Visual plasticity is classically considered to occur essentially in the primary and secondary
cortical areas. Subcortical visual areas such as the dorsal lateral geniculate nucleus (dLGN) …
cortical areas. Subcortical visual areas such as the dorsal lateral geniculate nucleus (dLGN) …
[HTML][HTML] Neuroplasticity-driven timing modulations revealed by ultrafast functional magnetic resonance imaging
Detecting neuroplasticity in global brain circuits in vivo is key for understanding myriad
processes such as memory, learning, and recovery from injury. Functional Magnetic …
processes such as memory, learning, and recovery from injury. Functional Magnetic …
Development of ocular dominance columns across rodents and other species: revisiting the concept of critical period plasticity
T Takahata - Frontiers in Neural Circuits, 2024 - frontiersin.org
The existence of cortical columns, regarded as computational units underlying both lower
and higher-order information processing, has long been associated with highly evolved …
and higher-order information processing, has long been associated with highly evolved …