Heme oxygenase-1: an anti-inflammatory effector in cardiovascular, lung, and related metabolic disorders

SW Ryter - Antioxidants, 2022 - mdpi.com
The heme oxygenase (HO) enzyme system catabolizes heme to carbon monoxide (CO),
ferrous iron, and biliverdin-IXα (BV), which is reduced to bilirubin-IXα (BR) by biliverdin …

The association of COVID-19 severity and susceptibility and genetic risk factors: A systematic review of the literature

A Ishak, M Mehendale, MM AlRawashdeh… - Gene, 2022 - Elsevier
Background COVID-19 is associated with several risk factors such as distinct ethnicities
(genetic ancestry), races, sexes, age, pre-existing comorbidities, smoking, and genetics. The …

The renin-angiotensin system: a key role in SARS-CoV-2-induced COVID-19

G El-Arif, A Farhat, S Khazaal, C Annweiler, H Kovacic… - Molecules, 2021 - mdpi.com
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative
agent of coronavirus disease 2019 (COVID-19), was first identified in Eastern Asia (Wuhan …

Vitamin D supplementation and Covid‐19 outcomes: a systematic review, meta‐analysis and meta‐regression

TI Hariyanto, D Intan, JE Hananto, H Harapan… - 2022 - Wiley Online Library
Vitamin D has many protective properties and potential role against acute lung injury. Low
serum vitamin D is associated with high risk of pneumonia and development of acute …

The complexity of SARS-CoV-2 infection and the COVID-19 pandemic

MK da Silva Torres, CDA Bichara… - Frontiers in …, 2022 - frontiersin.org
The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) led to the death of millions of people worldwide and thousands more infected individuals …

Association between angiotensinogen (AGT), angiotensin-converting enzyme (ACE) and angiotensin-II receptor 1 (AGTR1) polymorphisms and COVID-19 infection in …

HR Kouhpayeh, F Tabasi, M Dehvari, M Naderi… - Translational medicine …, 2021 - Springer
Background The COVID-19 pandemic remains an emerging public health crisis with serious
adverse effects. The disease is caused by severe acute respiratory syndrome coronavirus-2 …

Immunoinformatics-based multi-epitope vaccine design for the re-emerging monkeypox virus

M Farzan, M Farzan, Y Mirzaei, S Aiman… - International …, 2023 - Elsevier
Abstract Background On May 7, 2022, WHO reported a new monkeypox case. By May 2023
over 80,000 cases had been reported worldwide outside previously endemic nations.(This …

ACE2 polymorphisms impact COVID-19 severity in obese patients

N Jalaleddine, A Bouzid, M Hachim… - Scientific Reports, 2022 - nature.com
A strong association between obesity and COVID-19 complications and a lack of prognostic
factors that explain the unpredictable severity among these patients still exist despite the …

COVID-19 susceptibility, severity, clinical outcome and Toll-like receptor (7) mRNA expression driven by TLR7 gene polymorphism (rs3853839) in middle-aged …

SM El-Hefnawy, HA Eid, RG Mostafa, SS Soliman… - Gene Reports, 2022 - Elsevier
Background Toll-like receptors are implicated in the pathophysiology of the severe acute
respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory disease …

VDR gene polymorphisms are associated with the increased susceptibility to COVID‐19 among iranian population: A case‐control study

A Jafarpoor, SM Jazayeri… - International Journal …, 2022 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is an infectious disease caused by the
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), but the pathogenesis is …