HLA-G molecules: from maternal-fetal tolerance to tissue acceptance.

ED Carosella, P Moreau, J Le Maoult… - Advances in …, 2003 - europepmc.org
Over the past few years, HLA-G, the non-classical HLA class I molecule, has been the center
of investigations that have led to the description of its specific structural and functional …

HLA-G in human reproduction: aspects of genetics, function and pregnancy complications

TVF Hviid - Human reproduction update, 2006 - academic.oup.com
The non-classical human leukocyte antigen (HLA) class Ib genes, HLA-E,-G and-F, are
located on chromosome 6 in the human major histocompatibility complex (MHC). HLA class …

HLA‐G expression in early embryos is a fundamental prerequisite for the obtainment of pregnancy

B Fuzzi, R Rizzo, L Criscuoli, I Noci… - European journal of …, 2002 - Wiley Online Library
Different mechanisms mediated by the expression of the HLA‐class Ib HLA‐G products are
suggested to account for the induction of immune tolerance against the paternal antigens of …

Identification of HLA-G7 as a new splice variant of the HLA-G mRNA and expression of soluble HLA-G5,-G6, and-G7 transcripts in human transfected cells

P Paul, FA Cabestre, S Lefebvre, I Khalil-Daher… - Human immunology, 2000 - Elsevier
The nonclassical HLA-G primary transcript is alternatively spliced to generate several
mRNAs that have the capacity to encode four membrane bound isoforms, namely HLA-G1 …

HLA class I antigen abnormalities and immune escape by malignant cells

B Seliger, T Cabrera, F Garrido, S Ferrone - Seminars in cancer biology, 2002 - Elsevier
Abbreviations used in this paper: APM, antigen processing machinery; β2m, β2
microglobulin; bp, base pair; CTL, cytotoxic T lymphocytes; ER, endoplasmic reticulum; HC …

Embryonic soluble HLA-G as a marker of developmental potential in embryos

I Noci, B Fuzzi, R Rizzo, L Melchiorri… - Human …, 2005 - academic.oup.com
BACKGROUND: In human reproduction, embryo implantation is complex and poorly
understood. At present, no single markers are used in routine treatment to assay …

The molecular and functional characteristics of HLA-G and the interaction with its receptors: where to intervene for cancer immunotherapy?

JVD Attia, CE Dessens, R van de Water… - International journal of …, 2020 - mdpi.com
Human leukocyte antigen G (HLA-G) mediates maternal-fetal immune tolerance. It is also
considered an immune checkpoint in cancer since it may mediate immune evasion and thus …

Tumor-specific up-regulation of the nonclassical class I HLA-G antigen expression in renal carcinoma

EC Ibrahim, N Guerra, MJT Lacombe, E Angevin… - Cancer research, 2001 - AACR
HLA-G is a nonclassical class I antigen mainly expressed at the maternofetal interface
during pregnancy where it is thought to downmodulate maternal immune response against …

Some basic aspects of HLA‐G biology

E Alegre, R Rizzo, D Bortolotti… - Journal of …, 2014 - Wiley Online Library
Human leukocyte antigen‐G (HLA‐G) is a low polymorphic nonclassical HLA‐I molecule
restrictively expressed and with suppressive functions. HLA‐G gene products are quite …

Functional role of human leukocyte antigen-G up-regulation in renal cell carcinoma

J Bukur, V Rebmann, H Grosse-Wilde, H Luboldt… - Cancer research, 2003 - AACR
The nonclassical HLA-G molecule exhibits a limited tissue distribution and exerts multiple
immune regulatory functions. Recent studies indicate that HLA-G expression plays a key …