Epitope-based DNA vaccine development is one application of bioinformatics or in silico
studies, that is, computational methods, including mathematical, chemical, and biological …

Vaccination is historically one of the most important medical interventions for the prevention
of infectious disease. Previously, vaccines were typically made of rather crude mixtures of …

Zika virus (ZIKV), a mosquito-borne flavivirus, causes devastating congenital birth defects.
We isolated a human monoclonal antibody (mAb), ZKA190, that potently cross-neutralizes …

Traditional vaccines use inactivated or weakened forms of pathogens which could have side
effects and inadequate immune responses. To overcome these challenges, phage display …

Monoclonal antibodies have become an important class of therapeutics in the last 30 years.
Because the mechanism of action of therapeutic antibodies is intimately linked to their …

Technological revolutions in several fields have pushed the boundaries of vaccine design
and provided new avenues for vaccine development. Next-generation vaccine platforms …

The unique combinations of biological, nutritional and functional properties in proteins make
them important food ingredients with the capacity to provide a range of diverse and highly …

Therapeutic antibodies constitute one of the fastest areas of growth in the field of biologic
drugs. A molecular understanding of how antibodies interact with their target antigens is …

Abstract Microcystin-LR (MC-LR) is one of the most worldwide harmful cyanobacterial toxins.
A lots of antibodies against MC-LR have been generated and characterized. However, the …

In Brazil and in other tropical areas Zika virus infection was directly associated with clinical
complications as microcephaly in newborn children whose mothers were infected during …