Non-alcoholic steatohepatitis (NASH) develops from non-alcoholic fatty liver disease
(NAFLD). Currently, around 25% of the population is estimated to have NAFLD, and 25% of …

Obesity predisposes individuals to the development of insulin resistance in skeletal muscle
and the liver, and researchers have recently proposed two mechanisms by which excess …

Ageing, like obesity, is often associated with alterations in metabolic and inflammatory
processes resulting in morbidity from diseases characterised by poor metabolic control …

Rosacea is a chronic relapsing inflammatory skin disease with high prevalence worldwide.
Recent research suggests that dysregulation of innate and adaptive immune pathways as …

Sesquiterpene lactones (SLs) are the active constituents of a variety of medicinal plants
used in traditional medicine for the treatment of inflammatory diseases. In recent years, the …

Traumatic brain injury (TBI) is a leading cause of death and disability in young adults
worldwide. TBI survival is associated with persistent neuropsychiatric and neurological …

Although multiple cell types are present in the rheumatoid joint, the fibroblast-like synovial
cell (FLS) is among the most prominent. It is now appreciated that the FLS is not only space …

The outbreak of the coronavirus disease 2019 (COVID-19) pandemic has caused a global
public health crisis. Viral infections may predispose pregnant women to a higher rate of …

Vascular endothelium is a major target of actions of the proinflammatory cytokine tumor
necrosis factor (TNF). Increasingly, the intracellular pathways that are activated in response …

Aging is a complex biological process that is characterized by low-grade inflammation,
called inflammaging. Aging affects multiple organs including eye and lacrimal gland. Tumor …