Self-healing injectable hydrogels for tissue regeneration

P Bertsch, M Diba, DJ Mooney… - Chemical …, 2022 - ACS Publications
Biomaterials with the ability to self-heal and recover their structural integrity offer many
advantages for applications in biomedicine. The past decade has witnessed the rapid …

Hydrogel‐based growth factor delivery platforms: strategies and recent advances

BH Shan, FG Wu - Advanced Materials, 2024 - Wiley Online Library
Growth factors play a crucial role in regulating a broad variety of biological processes and
are regarded as powerful therapeutic agents in tissue engineering and regenerative …

[HTML][HTML] Injectable hydrogels in central nervous system: Unique and novel platforms for promoting extracellular matrix remodeling and tissue engineering

E Hasanzadeh, A Seifalian, A Mellati, J Saremi… - Materials Today Bio, 2023 - Elsevier
Repairing central nervous system (CNS) is difficult due to the inability of neurons to recover
after damage. A clinically acceptable treatment to promote CNS functional recovery and …

Recent advance in bioactive hydrogels for repairing spinal cord injury: material design, biofunctional regulation, and applications

Z Sun, D Zhu, H Zhao, J Liu, P He, X Luan, H Hu… - Journal of …, 2023 - Springer
Functional hydrogels show potential application in repairing spinal cord injury (SCI) due to
their unique chemical, physical, and biological properties and functions. In this …

Construction of injectable silk fibroin/polydopamine hydrogel for treatment of spinal cord injury

S Chen, S Liu, L Zhang, Q Han, H Liu, J Shen… - Chemical Engineering …, 2020 - Elsevier
Injectable hydrogels have potential applications for regenerating the injured spinal cord, but
their performance needs to be further improved. In this study, an injectable silk …

Release of O-GlcNAc transferase inhibitor promotes neuronal differentiation of neural stem cells in 3D bioprinted supramolecular hydrogel scaffold for spinal cord …

X Liu, S Song, Z Chen, C Gao, Y Li, Y Luo, J Huang… - Acta biomaterialia, 2022 - Elsevier
Precise fabrication of biomimetic three-dimensional (3D) structure and effective neuronal
differentiation under the pathological environment are the key to neural stem cell (NSC) …

Nerve growth factor-laden anisotropic silk nanofiber hydrogels to regulate neuronal/astroglial differentiation for scarless spinal cord repair

X Gao, W Cheng, X Zhang, Z Zhou, Z Ding… - … Applied Materials & …, 2022 - ACS Publications
Scarless spinal cord regeneration remains a challenge due to the complicated
microenvironment at lesion sites. In this study, the nerve growth factor (NGF) was …

[HTML][HTML] Self-assembling peptide hydrogels functionalized with LN-and BDNF-mimicking epitopes synergistically enhance peripheral nerve regeneration

S Yang, C Wang, J Zhu, C Lu, H Li, F Chen, J Lu… - Theranostics, 2020 - ncbi.nlm.nih.gov
The regenerative capacity of the peripheral nervous system is closely related to the role that
Schwann cells (SCs) play in construction of the basement membrane containing multiple …

Regenerative rehabilitation with conductive biomaterials for spinal cord injury

EA Kiyotake, MD Martin, MS Detamore - Acta biomaterialia, 2022 - Elsevier
The individual approaches of regenerative medicine efforts alone and rehabilitation efforts
alone have not yet fully restored function after severe spinal cord injury (SCI). Regenerative …

Harnessing the power of biological macromolecules in hydrogels for controlled drug release in the central nervous system: A review

S Ghosh, S Ghosh, H Sharma, R Bhaskar… - International Journal of …, 2024 - Elsevier
Hydrogels have immense potential in revolutionizing central nervous system (CNS) drug
delivery, improving outcomes for neurological disorders. They serve as promising tools for …