Cancers are complex ecosystems composed of malignant cells embedded in an intricate
microenvironment made of different non-transformed cell types and extracellular matrix …

Infrared chemical imaging is a rapidly emerging field with new advances in instrumentation,
data acquisition and data analysis. These developments have had significant impact in …

IR spectroscopy is an excellent method for biological analyses. It enables the
nonperturbative, label-free extraction of biochemical information and images toward …

In this study we present an image analysis methodology capable of quantifying
morphological changes in tissue collagen fibril organization caused by pathological …

Fourier transform infrared (FTIR) spectroscopy is a powerful tool for analyzing the
biochemical properties of biological samples such as proteins, cellular materials, and …

In the last two decades the field of infrared spectroscopy has seen enormous advances in
both instrumentation and the development of bioinformatic methods for spectral analysis …

In this chapter, we describe biomedical applications of infrared microscopic imaging applied
to human tissue sections. The central focus is human diseases including cervical cancer …

IR absorption imaging, especially using Fourier transform IR (FT-IR) imaging spectrometers,
is an emerging modality for biomedical applications. As opposed to current techniques that …

Diffuse malignant mesothelioma (DMM) is a heterogeneous malignant neoplasia
manifesting with three subtypes: epithelioid, sarcomatoid and biphasic. DMM exhibit a high …

Histopathological differentiation between severe urocystitis with reactive urothelial atypia
and carcinoma in situ (CIS) can be difficult, particularly after a treatment that deliberately …